Results 141 to 150 of about 87,393 (252)

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Bilateral Lower Limb Acute Compartment Syndrome Related to Drug Abuse: Two Case Reports. [PDF]

Plast Reconstr Surg Glob Open
Matsuda T, Ono S, Murakami T, Ogawa R.
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Case report: morbid obesity and lithotomy positioning: a high-risk triad with GCS leading to severe rhabdomyolysis with impending acute compartment syndrome following ovarian cancer cytoreduction. [PDF]

BMC Surg
Sun X, Tao W, Xu Z.
europepmc   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Risk factors and outcomes of acute compartment syndrome after coronary artery bypass grafting: a matched case-control study. [PDF]

BMC Surg
Wu T, Xu S, Liu C, Li H, Meng X.
europepmc   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

Ropivacaine-based Regional Anesthesia Exerts Muscle-protective Effects Despite Elevated Compartment Pressure in a Porcine Model of Acute Compartment Syndrome. [PDF]

Anesthesiology
Fritsch G, Thaler P, Ferguson J, Thumfart H, Grillari J, Osuchowski M, Woisetschlaeger G, Hoegler S, Gutasi A, Zipperle J.   +9 more
europepmc   +1 more source

From Negative Duplex to Phlegmasia in Minutes: Bedside POCUS Identifies Rapid Thrombosis Unmasking Underlying May–Thurner Syndrome

Journal of Clinical Ultrasound, EarlyView.
Point‐of‐care‐ultrasound revealed an evolving acute noncompressible deep vein thrombosis (asterisks) in the left lower extremity veins (right panel) that was not evident on duplex ultrasound 14 min prior (left panel; asterisks demonstrate compressed veins). The patient was treated emergently and found to have May–Thurner syndrome.
Anthony Unger
wiley   +1 more source

Isolated Fibula Fracture With Development of Acute Compartment Syndrome. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Bortman JM, Buchanan MW, Freccero DM.
europepmc   +1 more source