Results 161 to 170 of about 2,625,804 (282)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Acute compartment syndrome in <i>Bothrops atrox</i> envenomation: a case-control study in the Brazilian Amazon. [PDF]

open access: yesJ Venom Anim Toxins Incl Trop Dis
do Nascimento GOB   +7 more
europepmc   +1 more source

B, N‐Co Doped Porous Carbon Nanotubes Supported Cu Single Atoms and B‐Doped Cu Nanoparticles for High‐Performance Electrocatalytic NO3RR and Zn‐Nitrate Batteries

open access: yesCarbon Energy, EarlyView.
The ToC image shows a porous B, N‐doped carbon nanotube decorated with B‐doped Cu nanoparticles for nitrate‐to‐ammonia conversion. The unique structure enhances charge transport, promotes the adsorption and activation of key intermediates, alters the rate‐determining step, suppresses hydrogen evolution, and improves NH3 yield and Faradaic efficiency ...
Xiangding Li   +7 more
wiley   +1 more source

Acute compartment syndrome following Bitis viper envenomation: a literature review with case reports. [PDF]

open access: yesInt J Emerg Med
Baliarová D   +5 more
europepmc   +1 more source

From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems

open access: yesChemistry – A European Journal, EarlyView.
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui   +5 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Acute Compartment Syndrome Post-Thrombolysis for Acute Pulmonary Embolism-A Case Report. [PDF]

open access: yesClin Case Rep
Ziblim AM   +9 more
europepmc   +1 more source

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

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