Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Acute compartment syndrome in <i>Bothrops atrox</i> envenomation: a case-control study in the Brazilian Amazon. [PDF]
do Nascimento GOB +7 more
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The ToC image shows a porous B, N‐doped carbon nanotube decorated with B‐doped Cu nanoparticles for nitrate‐to‐ammonia conversion. The unique structure enhances charge transport, promotes the adsorption and activation of key intermediates, alters the rate‐determining step, suppresses hydrogen evolution, and improves NH3 yield and Faradaic efficiency ...
Xiangding Li +7 more
wiley +1 more source
Acute compartment syndrome following Bitis viper envenomation: a literature review with case reports. [PDF]
Baliarová D +5 more
europepmc +1 more source
From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui +5 more
wiley +1 more source
Acute Compartment Syndrome Following Repeated Calf Kicks in an Elite-Level Kickboxing Athlete: A Case Report of a Rare Non-Fracture-Related Complication. [PDF]
Beca S +4 more
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Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
Acute Compartment Syndrome Post-Thrombolysis for Acute Pulmonary Embolism-A Case Report. [PDF]
Ziblim AM +9 more
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From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley +1 more source
Atraumatic acute compartment syndrome secondary to prolonged intoxication induced recumbency: a case series. [PDF]
Greenspan J +3 more
europepmc +1 more source

