Results 111 to 120 of about 225,090 (265)

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan, Deng Liu, Wuhen Xu, Yang Li, Juanli Hu, Oppermann Henry, Alexander Fuchs, Rami Abou Jamra, Zhen Liu, Mei He, Yuanlu Chen, Shengnan Wu, Xiaohuan Dong, Yiqiao Chen, Pengchao Wang, Weiyue Gu, Han Jing, Yabing Tang, Ya‐Jie Wang, Xiao Mao, Neng Xiao   +20 more
wiley   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

Equine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock, John Grewar, Richard Newton   +2 more
wiley   +1 more source

NHG-guideline acute cough [PDF]

, 2011
Acute cough is one of the most common reasons for patients to visit a general practitioner. In this revised guideline acute cough is defined as cough lasting less than 3 weeks at presentation.
Verheij, Th J.M., Prins, J. M., Verlee, E., Bindels, P. J.; id_orcid, Hopstaken, R. M., Ponsioen, B. P., Thiadens, H. A., Sachs, A. P.E., Salomé, Ph L.   +8 more
core   +2 more sources

Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)

, 2006
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far.
David A Groneberg, Wagner, Ulrich, Fischer, Axel, Groneberg, Jan David Alexander, Groneberg David A, Welte, Tobias, Fehmann Hans-Christoph, Staats Petra, Axel Fischer, Welte Tobias, Fischer Axel, Ulrich Wagner, Tobias Welte, Fehmann, Hans-Christoph, Petra Staats, Staats, Petra, Hans-Christoph Fehmann, Wagner Ulrich   +17 more
core   +1 more source

Three‐Dimensional Magnetic Multi‐Metallic Nanozymes With Colorimetric and Catalytic Amplification for Rapid and Highly‐Sensitive Detection of Influenza A

Exploration, EarlyView.
The application of nanozymes in LFIA greatly improved the situation of insufficient colorimetric signals by catalytic reaction. 3D magnetic multi‐metallic nanozymes integrated the characteristics of great magnetism, enhanced colorimetric signal, and outstanding POD‐like activity, and were applied to LFIA for rapid and accurate detection of Influenza A ...
Zhenzhen Liu, Pengyou Zhou, Xiaofei Jia, Xiaoxian Liu, Yong Yang, Yansong Sun, Rui Xiao   +6 more
wiley   +1 more source

Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a Prospective Multicentre Cohort Study With 6‐Month Follow‐Up

Head &Neck, EarlyView.
ABSTRACT Background Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited. Methods This prospective cohort study included 34 HNC survivors (≥ 1 year post‐treatment) who completed a 3‐week intensive ...
J. I. Oldenbeuving, L. van der Molen, J. T. Groothuis, J. G. Kalf   +3 more
wiley   +1 more source

Honey for acute cough in children - a systematic review. [PDF]

Eur J Pediatr, 2023
Kuitunen I, Renko M.
europepmc   +1 more source

Effectiveness of a cough management algorithm at the transitional phase from acute to chronic cough in Australian children aged <15 years: protocol for a randomised controlled trial

, 2017
Introduction Acute respiratory infections (ARIs) are leading causes of hospitalisation in Australian children and, if recurrent, are associated with increased risk of chronic pulmonary disorders later in life.
Anne Connor, Toombs, Maree, Oon Meng kar, Chang, Anne B., Rablin, Sheree, Torzillo, Paul J, Jennie Anderson, Anne B Chang, Keith Grimwood, Chang, Anne B, O'Grady, Kerry-Ann F, Grimwood, Keith, Torzillo, Paul J., Buntain, Helen, Anderson, Jennie, O'Grady, Kerry-Ann F., Connor, Anne, Whiley, David, Meng Kar, Oon, Maree Toombs, Helen Buntain, Paul J Torzillo, Whiley, David M., Sloots, Theo P, Michael Otim, Don Adsett, Sloots, Theo P., Adsett, Don, Kerry-Ann F O'Grady, Otim, Michael, David Whiley, Kar, Oon Meng, Sheree Rablin, Theo P Sloots   +33 more
core   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source