Results 1 to 10 of about 199,011 (303)

From bench to bedside: The role of cough hypersensitivity in chronic cough

Clinical and Translational Medicine, 2023
Background Chronic cough is a burdensome condition characterized by persistent cough lasting longer than 8 weeks. Chronic cough can significantly affect quality of life, physical function and productivity, with many people troubled with a cough that ...
Matthew G. Drake, Lorcan P. McGarvey, Alyn H. Morice   +2 more
doaj   +2 more sources

Cough hypersensitivity and chronic cough

Nature Reviews Disease Primers, 2022
Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat because many pulmonary and extrapulmonary conditions can present with chronic cough, and cough can also be present without any identifiable underlying cause or be refractory to therapies that improve associated conditions.
Kian Fan Chung, Lorcan McGarvey, Woo-Jung Song, Anne B. Chang, Kefang Lai, Brendan J. Canning, Surinder S. Birring, Jaclyn A. Smith, Stuart B. Mazzone   +8 more
openaire   +6 more sources

Differences in Causes, Severity, and Treatment Outcomes Between Women and Men with Chronic Cough [PDF]

Advances in Respiratory Medicine
A chronic cough, defined as a cough persisting for more than eight weeks in adults, is a common clinical problem with a significant impact on patients’ quality of life.
Aleksandra Marchwińska, Katarzyna Mazurek, Katarzyna Białek-Gosk, Elżbieta M. Grabczak, Olga Truba, Karolina Klimowicz, Marta Dąbrowska   +6 more
doaj   +2 more sources

Cough persistence in adults with chronic cough: A 4-year retrospective cohort study

Allergology International, 2020
Background: There is very limited evidence regarding long-term prognosis of chronic cough. We examined longitudinal outcomes among patients with chronic cough, and explored predictors of cough persistence.
Sung-Yoon Kang, Woo-Jung Song, Ha-Kyeong Won, Soo Jie Chung, Ju-Young Kim, Heung-Woo Park, Alyn H. Morice, Sang-Heon Cho   +7 more
doaj   +3 more sources

Female predominance in chronic cough: biological sex–related factors, mechanisms, and therapeutic targets—a narrative review [PDF]

Frontiers in Medicine
Chronic cough—defined in adults as cough lasting ≥8 weeks—shows higher prevalence in women. Accumulating evidence supports a cough hypersensitivity phenotype with peripheral and central drivers that may vary by biological sex.
Aibo Zheng, Kai Sun, Wenjun Li, Zhiyu Chen, Yuting Li, Wei Wu, Jie Gan   +6 more
doaj   +2 more sources

Management of chronic cough

Lancet, The, 2008
Cough that remains unexplained after basic clinical assessment is a common reason for referral to secondary care. Much of the evidence about management of isolated chronic cough is derived from case series; this evidence suggests that isolated chronic cough is usually due to asthma, gastro-oesophageal reflux disease, and upper airway conditions, and ...
Ian D Pavord, Kian Fan Chung
exaly   +3 more sources

Somatically evoked cough responses help to identify patients with difficult-to-treat chronic cough: a six-month observational cohort studyResearch in context

EClinicalMedicine, 2023
Summary: Background: Recently we identified in patients with chronic cough a sensory dysregulation via which the urge-to-cough (UTC) or coughing are evoked mechanically from “somatic points for cough” (SPCs) in the neck and upper trunk.
Federico Lavorini, Guja Bernacchi, Carlo Fumagalli, Marianna Noale, Stefania Maggi, Donatella Mutolo, Eliana Cinelli, Giovanni A. Fontana   +7 more
doaj   +1 more source

Understanding the economic burden of chronic cough: a systematic literature review

BMC Pulmonary Medicine, 2023
Chronic cough (CC) is associated with high healthcare resource utilization (HCRU) due to challenges in diagnosis and treatment and is anticipated to have a substantial economic impact.
Vishal Bali, Ada Adriano, Aidan Byrne, Katherine G. Akers, Andrew Frederickson, Jonathan Schelfhout   +5 more
doaj   +1 more source

Web-based survey to evaluate the prevalence of chronic and subacute cough and patient characteristics in Japan

BMJ Open Respiratory Research, 2021
Background Cough lasting 3–8 weeks and more than 8 weeks are defined as subacute/prolonged cough and chronic cough, respectively. Japanese chronic cough population has not been well studied. This study aimed to describe the prevalence and characteristics
Yirong Chen, Keisuke Tobe, Shigeru Tokita, Takekazu Kubo, Kotoba Okuyama, Masashi Kikuchi, Jonathan Schelfhout, Machiko Abe   +7 more
doaj   +1 more source

Cough desensitization treatment for patients with refractory chronic cough: results of a second pilot randomized control trial

BMC Pulmonary Medicine, 2023
Objective The purpose of this study was to collect pilot efficacy data on a novel treatment for refractory chronic cough (RCC), which we call cough desensitization treatment (CDT).
Laurie J. Slovarp, Jane E. Reynolds, Sophia Tolbert, Sarah Campbell, Shannon Welby, Paige Morkrid   +5 more
doaj   +1 more source