Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents [PDF]
Scientific Reports, 2021 Glioblastoma (GBM) is an aggressive brain tumor with a strong tendency of relapse and resistance to chemotherapy, but we currently lack non-toxic agents that effectively treat GBM.
Sook-Ja Lee +3 more
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Molecules, 2019 Natural products play an important role in drug discovery. This work employed a natural product 1-methylhydantoin as the lead compound to develop novel dual-active drugs. 1-Methylhydantoin was isolated from Oviductus Ranae, which is a traditional Chinese
Yang Xu +8 more
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Comparative Analysis of Classic and Novel Antitussives on Cough Suppression in Guinea Pigs [PDF]
PharmaceuticsIntroduction: Cough is a common reflex that serves a protective role, but when persistent, it can severely affect patients’ quality of life. Despite its high prevalence, current treatment options remain limited.
Paula Montero +4 more
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Assessing the Safety of Carbon Dioxide Extracts of Acorus calamus Rhizomes and Calendula officinalis Flowers and the Antitussive Activity of the Tablet Dosage Form ‘Exkair’ and Granules ‘Zerp-Ak-Broncho’ Developed on Their Basis [PDF]
PharmaceuticalsBackground: The growing demand for safe and effective phytopharmaceuticals underscores the importance of studying regionally available medicinal plants. Acorus calamus L. and Calendula officinalis L., widely distributed in the Republic of Kazakhstan, are
Galiya Ibadullayeva +10 more
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Physiological mechanisms and therapeutic targets in chronic cough. [PDF]
Physiol RepAbstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
Brown JC +3 more
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Monitoring OTC drug sales for early detection of respiratory infectious disease outbreaks [PDF]
Frontiers in Public HealthBackgroundIn recent years, over-the-counter (OTC) drug sales have emerged as a novel indicator for symptom monitoring, attracting widespread attention in public health research globally.
Junjie Li +8 more
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Use of Antitussive, Mucolytic Agents and Expectorants [PDF]
Journal of the Korean Medical Association, 2005 Cough associated with acute or chronic respiratory conditions is common in patients of all ages. Current antitussive agents are classified broadly according to their site of action as either central or peripheral, although many antitussives act in both ...
안철민
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PHARMACOLOGICAL STUDIES ON NEW SYNTHETIC ANTITUSSIVE AGENTS
Canadian Journal of Biochemistry and Physiology, 1958 In an attempt to overcome the inherent disadvantage of narcotic antitussive therapy, three basic alkoxy-alkyl esters of phenothiazine-10-carboxylic acid were synthesized and tested for pharmacological activity. These compounds possessed antitussive activity in the cat in the range of activity of codeine.
C I, CHAPPEL, M G, STEGEN, G A, GRANT
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A case of serotonin syndrome following the reintroduction of aripiprazole after dextromethorphan overdose [PDF]
PCN ReportsBackground Serotonin syndrome is a potentially life‐threatening condition that arises from excessive serotonergic activity. Dextromethorphan (DXM), commonly used as a non‐prescription antitussive, can induce serotonin syndrome when taken in high doses or
Naoko Saito +4 more
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Correction: Altyar et al. Malva parviflora Leaves and Fruits Mucilage as Natural Sources of Anti-Inflammatory, Antitussive and Gastro-Protective Agents: A Comparative Study Using Rat Models and Gas Chromatography. Pharmaceuticals 2022, 15, 427 [PDF]
PharmaceuticalsIn the original publication [...]
Ahmed E. Altyar +9 more
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