Results 1 to 10 of about 5,757 (219)

Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents [PDF]

Scientific Reports, 2021
Glioblastoma (GBM) is an aggressive brain tumor with a strong tendency of relapse and resistance to chemotherapy, but we currently lack non-toxic agents that effectively treat GBM.
Sook-Ja Lee, Seon-Yong Yeom, Jee-Young Lee, Chaehwa Park   +3 more
doaj   +2 more sources

Comparative Analysis of Classic and Novel Antitussives on Cough Suppression in Guinea Pigs [PDF]

Pharmaceutics
Introduction: Cough is a common reflex that serves a protective role, but when persistent, it can severely affect patients’ quality of life. Despite its high prevalence, current treatment options remain limited.
Paula Montero, Inés Roger, Erika Esposito, Javier Milara, Julio Cortijo   +4 more
doaj   +2 more sources

Monitoring OTC drug sales for early detection of respiratory infectious disease outbreaks [PDF]

Frontiers in Public Health
BackgroundIn recent years, over-the-counter (OTC) drug sales have emerged as a novel indicator for symptom monitoring, attracting widespread attention in public health research globally.
Junjie Li, Chen Wu, Kui Liu, Qinbao Lu, Xinyi Wang, Zheyuan Ding, Tianying Fu, Xuefeng Jiang, Haocheng Wu   +8 more
doaj   +2 more sources

A case of serotonin syndrome following the reintroduction of aripiprazole after dextromethorphan overdose [PDF]

PCN Reports
Background Serotonin syndrome is a potentially life‐threatening condition that arises from excessive serotonergic activity. Dextromethorphan (DXM), commonly used as a non‐prescription antitussive, can induce serotonin syndrome when taken in high doses or
Naoko Saito, Nobuhiko Noguchi, Maki Toida, Masatoshi Miyauchi, Takeshi Asami   +4 more
doaj   +2 more sources

Correction: Altyar et al. Malva parviflora Leaves and Fruits Mucilage as Natural Sources of Anti-Inflammatory, Antitussive and Gastro-Protective Agents: A Comparative Study Using Rat Models and Gas Chromatography. Pharmaceuticals 2022, 15, 427 [PDF]

Pharmaceuticals
In the original publication [...]
Ahmed E. Altyar, Ans Munir, Saiqa Ishtiaq, Muhammad Rizwan, Khizar Abbas, Osama Kensara, Sameh S. Elhady, Waleed Y. Rizg, Fadia S. Youssef, Mohamed L. Ashour   +9 more
doaj   +2 more sources

The Potential of Topical Phytopharmaceuticals for the Management of COVID-19-Associated Cough from the Perspective of Traditional Persian Medicine [PDF]

Iranian Journal of Medical Sciences, 2022
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into the most severe pandemic affecting millions of people worldwide.
Parmis Badr, Fatemeh Etemadpour, Reyhaneh Chini, Nikoo Khalili Moghadam   +3 more
doaj   +1 more source

Features of cough therapy in children

Медицинский совет, 2021
This article discusses the problem of cough in children as one of the symptoms of a complicated course of acute respiratory infection. The data on the peculiarities of the course of cough in children depending on the cause, the level of damage, and age ...
I. N. Kholodova
doaj   +1 more source

The effectiveness of gabapentin and gabapentin/montelukast combination compared with dextromethorphan in the improvement of COVID‐19‐ related cough: A randomized, controlled clinical trial

The Clinical Respiratory Journal, 2022
Introduction Cough is one of the most common presenting symptoms of COVID‐19, which can persist for weeks or months. Objective The goal of this study was to evaluate the effectiveness of gabapentin (GBT) alone and in combination with montelukast (MTL ...
Rasool Soltani, Sara Nasirharandi, Farzin Khorvash, Maryam Nasirian, Kian Dolatshahi, Atousa Hakamifard   +5 more
doaj   +1 more source

A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough

Allergology International, 2022
Background: In two phase 3, global clinical trials (COUGH-1 and COUGH-2), the P2X3-receptor antagonist gefapixant significantly reduced objective 24-h cough frequency in participants with refractory or unexplained chronic cough (RCC or UCC) at a dosage ...
Akio Niimi, Hironori Sagara, Masashi Kikuchi, Ichiro Arano, Asako Sato, Masayoshi Shirakawa, Carmen La Rosa, David Muccino   +7 more
doaj   +1 more source

Coughing in Small Animal Patients

Frontiers in Veterinary Science, 2020
Cough is one of the most common complaints in human medicine. In veterinary medicine cough is equally frequent and plays a significant role in an owner's perception of their pet's quality of life.
Brisa M. Hsieh, Alicia K. Beets
doaj   +1 more source