Results 31 to 40 of about 1,499,897 (194)

Structure−Antitussive Activity Relationships of Naltrindole Derivatives. Identification of Novel and Potent Antitussive Agents

, 2016
We have previously reported antitussive effects of naltrindole (NTI), a typical δ opioid receptor antagonist, in a rat model. The ED50 values of NTI by intraperitoneal and peroral injections were 104 μg/kg and 1840 μg/kg, respectively, comparable to ...
Koji Kawai (2176478), Satoshi Sakami (2424862), Tsuyoshi Ito (2424853), Kuniaki Kawamura (2424865), Mayumi Nakajima (2320915), Masayuki Maeda (2424859), Hiroshi Nagase (719027), Hideaki Fujii (1503139), Shinya Ueno (143851), Takumi Aoki (2424856), Ko Hasebe (2394280), Takashi Endo (19218), Junzo Kamei (828029)   +12 more
core   +1 more source

Effectiveness of budesonide formoterol fixed-dose combination MDI in reducing cough symptoms in COVID-19 patients: A real-world evidence study

Lung India, 2023
Background: Cough is a wearisome and exasperating symptom affecting the daily life of the infected patient. Cough due to coronavirus disease 2019 (COVID-19) causes excessive morbidity in human populations globally.
Shambo Samrat Samajdar, Shatavisa Mukherjee, Saibal Moitra, Jyotirmoy Pal, Shashank Joshi, Santanu Kumar Tripathi   +5 more
doaj   +1 more source

Diagnosis and treatment of cough in children

Медицинский совет, 2017
Cough is one of the most common reasons for seeking medical care and may be one of the manifestations of the respiratory tract pathology and various extrapulmonary diseases.
N. G. Kolosova, M. D. Shakhnazarova, S. I. Shatalina   +2 more
doaj   +1 more source

Antitussive agents as N-methylaspartate antagonists: further studies

, 1989
The relative potencies of ketamine and the morphinan derivatives dextrorphan, dextromethorphan, and levorphanol as antagonists of the excitatory actions of N-methylaspartate on rat spinal neurones in vivo were examined, both following their ...
John Church, Stephen N. Davies, David Lodge, Martyn G. Jones   +3 more
core   +1 more source

Ethnomedicinal, Phytochemical and Pharmacological Profile of Anthriscus sylvestris as an Alternative Source for Anticancer Lignans

Molecules, 2015
Anthriscus sylvestris (L.) Hoffm. is a wild herbaceous plant common in most temperate regions. It has been used traditionally to treat headaches, as a tonic, as antitussive, antipyretic, analgesic and diuretic.
Octavian Tudorel Olaru, George Mihai Niţulescu, Alina Orțan, Cristina Elena Dinu-Pîrvu   +3 more
doaj   +1 more source

Merger Efficiency and Coordinated Effects: Nothing to Sneeze at? Evidence From Cough and Cold Medicines in the Philippines

Southern Economic Journal, EarlyView.
ABSTRACT We investigate the competitive effects of a merger in the cough and cold medicines segment between GlaxoSmithKline (GSK) and Pfizer. The parties offered efficiency gains, and authorities concluded the merger would not lessen competition. Using product‐level data from the Philippines, we estimate a structural demand model to assess efficiency ...
Farasat A. S. Bokhari, Sean Ennis, Carlos Vega, Weijie Yan   +3 more
wiley   +1 more source

Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit

, 2010
We have previously shown that the caudal nucleus tractus solitarii is a site of action of some antitussive drugs and that the caudal ventral respiratory group (cVRG) region has a crucial role in determining both the expiratory and inspiratory components
Mutolo, Donatella, Bongianni, Fulvia, Cinelli, Elenia, Pantaleo, Tito, Donatella Mutolo, Fulvia Bongianni, Elenia Cinelli, Tito Pantaleo   +7 more
core   +1 more source

Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America

Molecules, 2018
The Verbenaceae family includes 2600 species grouped into 100 genera with a pantropical distribution. Many of them are important elements of the floras of warm-temperature and tropical regions of America.
Cristina M. Pérez Zamora, Carola A. Torres, María B. Nuñez   +2 more
doaj   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source