Results 21 to 30 of about 1,993,700 (294)

Multicentre, 2×2 factorial, randomised, open-label trial of neuromodulators and cough control therapy for refractory or unexplained chronic cough: the FORTITUDE trial protocol [PDF]

BMJ Open
Introduction While clinicians commonly prescribe neuromodulators for the treatment of refractory or unexplained chronic cough, no trials have directly compared these treatments.
Ana Oliveira, Gordon Guyatt, Alan G Kaplan, Anurag Bhalla, Dina Brooks, Elena Kum, Mélanie Bernier, Stephen K Field, Imran Satia, Robert Newman, Simon Couillard, Wafa Hassan, Geoff Strong, Andréanne Côté, Kim Smith, Sue Beaudin, Mustafa Al-Saiedy, Renata Mancopes, Ana Sofia Grave, Danica L Brister, Faye Johnston, Nada Popovic   +21 more
doaj   +2 more sources

Somatically evoked cough responses help to identify patients with difficult-to-treat chronic cough: a six-month observational cohort studyResearch in context

EClinicalMedicine, 2023
Summary: Background: Recently we identified in patients with chronic cough a sensory dysregulation via which the urge-to-cough (UTC) or coughing are evoked mechanically from “somatic points for cough” (SPCs) in the neck and upper trunk.
Federico Lavorini, Guja Bernacchi, Carlo Fumagalli, Marianna Noale, Stefania Maggi, Donatella Mutolo, Eliana Cinelli, Giovanni A. Fontana   +7 more
doaj   +1 more source

WAO-ARIA consensus on chronic cough - Part 1: Role of TRP channels in neurogenic inflammation of cough neuronal pathways [PDF]

, 2021
Background: Cough features a complex peripheral and central neuronal network. The function of the chemosensitive and stretch (afferent) cough receptors is well described but partly understood.
Azar, Cecilio R, Laidlaw, Tanya M, Bahna, Sami L, Al-Nesf, Maryam Ali Y, Nsouli, Talal M, Smith, Peter K, Yáñez, Anahí, Idriss, Samar A, Rouadi, Philip W, Hellings, Peter W, Sulaiman Al-Ahmad, Mona, Zaitoun, Fares H, Abou-Jaoude, Eliane, Hadi, Usamah M, Bousquet, Jean, et al.   +15 more
core   +2 more sources

Chronic cough due to occupational factors [PDF]

, 2006
Within the large variety of subtypes of chronic cough, either defined by their clinical or pathogenetic causes, occupational chronic cough may be regarded as one of the most preventable forms of the disease.
David A Groneberg, Groneberg, David A., Axel Fischer, Fischer, Axel, Fischer Axel, Wussow Anke, Nowak Dennis, Groneberg David A, Dennis Nowak, Nowak, Dennis, Anke Wussow, Wussow, Anke, Groneberg, Jan David Alexander   +12 more
core   +2 more sources

Cough desensitization treatment for patients with refractory chronic cough: results of a second pilot randomized control trial

BMC Pulmonary Medicine, 2023
Objective The purpose of this study was to collect pilot efficacy data on a novel treatment for refractory chronic cough (RCC), which we call cough desensitization treatment (CDT).
Laurie J. Slovarp, Jane E. Reynolds, Sophia Tolbert, Sarah Campbell, Shannon Welby, Paige Morkrid   +5 more
doaj   +1 more source

Web-based survey to evaluate the prevalence of chronic and subacute cough and patient characteristics in Japan

BMJ Open Respiratory Research, 2021
Background Cough lasting 3–8 weeks and more than 8 weeks are defined as subacute/prolonged cough and chronic cough, respectively. Japanese chronic cough population has not been well studied. This study aimed to describe the prevalence and characteristics
Yirong Chen, Keisuke Tobe, Shigeru Tokita, Takekazu Kubo, Kotoba Okuyama, Masashi Kikuchi, Jonathan Schelfhout, Machiko Abe   +7 more
doaj   +1 more source

Understanding the economic burden of chronic cough: a systematic literature review

BMC Pulmonary Medicine, 2023
Chronic cough (CC) is associated with high healthcare resource utilization (HCRU) due to challenges in diagnosis and treatment and is anticipated to have a substantial economic impact.
Vishal Bali, Ada Adriano, Aidan Byrne, Katherine G. Akers, Andrew Frederickson, Jonathan Schelfhout   +5 more
doaj   +1 more source

Chronic cough: is the end nigh?

, 2023
Chronic cough (lasting more than 8 weeks) is a common condition with substantial psychosocial impact. Despite huge efforts following robust guidelines, chronic cough in many patients remains refractory or unexplained (RU-CC).
Cho, PSP, Hirons, B, Birring, SS, Turner, R   +3 more
core   +1 more source

Chronic Cough

New England Journal of Medicine, 2016
A 63-year-old woman presents with a 1-year history of a chronic dry cough, associated with a sensation of “irritation” in the throat. Prolonged bouts of coughing are associated with stress urinary incontinence and occasionally end with retching and vomiting.
Smith, Jaclyn A.; id_orcid 0000-0001-8837-4928, Woodcock, Ashley   +1 more
openaire   +7 more sources

Chronic cough

Current Opinion in Supportive & Palliative Care, 2008
Chronic cough is common and distressing, especially against the background of life-threatening illness. It is a symptom that has received scant attention, often eclipsed by pain, breathlessness, nausea and vomiting.This paper reviews the recent literature in cough research: its mechanism, assessment and management.
Nagala S, Wilson JA
openaire   +5 more sources