Results 121 to 130 of about 1,507,605 (275)

A Proof‐of‐Concept Study of Language‐Stratified Assessment for Minimal Hepatic Encephalopathy: Integrating the Animal Naming Test and Serum IL‐6

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Minimal hepatic encephalopathy (MHE) involves subtle cognitive dysfunction and systemic inflammation and is associated with an increased risk of overt hepatic encephalopathy. The Animal Naming Test (ANT1) is a rapid semantic fluency tool for MHE assessment, but its performance across different primary spoken languages remains unclear.
Hsin‐Che Lin, Cheng Jen Chen, Tsung‐Han Wu, Po‐Wen Gu, Chun‐Yi Tsai, Wey‐Ran Lin, Chao‐Wei Hsu, Chun‐Yen Lin, Rong‐Nan Chien, Chien‐Hao Huang, Piero Amodio   +10 more
wiley   +1 more source

Cell death markers in patients with cirrhosis and acute decompensation

, 2019
The aims of this study were to determine the role of cell death in patients with cirrhosis and acute decompensation (AD) and acute on chronic liver failure (ACLF) using plasma‐based biomarkers. The patients studied were part of the CANONIC (CLIF Acute‐on‐
Macdonald, Stewart, Bachtiger, Patrik, Amorós, Àlex, Arroyo, Vicente, Mookerjee, Rajeshwar P., Caraceni, Paolo, Gerbes, Alexander L., Andreola, Fausto, Moreau, Richard, Ginès i Gibert, Pere, Pavesi, Marco, Zheng, Yu Bao, Jalan, Rajiv, Grønbaek, Henning, Solà, Elsa   +14 more
core   +2 more sources

Defining sagittal knee phenotypes via monopedal static anterior tibial translation. Part 1: Translating weight‐bearing sagittal position into clinical risk profiles

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Static anterior tibial translation (sATT) is a reproducible monopodal weight‐bearing radiographic parameter that reflects the resting sagittal position of the tibiofemoral joint. Distinct from manual laxity tests that quantify passive displacement limits, sATT captures the functional equilibrium of the tibia under physiological load ...
Mahmut Enes Kayaalp, Hamit Caglayan Kahraman, Tunay Erden, Christoph Lutter, Sven Scheffler, Omer Taser, Roland Becker, Michael T. Hirschmann, David H. Dejour   +8 more
wiley   +1 more source

Defining sagittal knee phenotypes via monopedal static anterior tibial translation. Part 2: The assessment‐led personalization (ALP) system for indication and correction target planning in slope‐reducing osteotomy

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Current decision‐making for slope‐reducing osteotomy (SRO) often relies on isolated posterior tibial slope (PTS) thresholds, potentially misidentifying patients with acquired soft‐tissue decompensation or possibly overtreating those with an asymptomatic, inherently hyperlax baseline.
Mahmut Enes Kayaalp, Hamit Caglayan Kahraman, Tunay Erden, Christoph Lutter, Sven Scheffler, Omer Taser, Roland Becker, Michael T. Hirschmann, David H. Dejour   +8 more
wiley   +1 more source

Intravenous nitrates in modern cardiology

Кардиоваскулярная терапия и профилактика, 2005
Nitrates are widely used in cardiology since XIX century. In modern urgent cardiology, intravenous nitrates are administered most often. Numerous studies confirm high clinical efficacy and safety of intravenous nitrates in acute coronary syndromes, acute
I. V. Zhirov, S. N. Tereshchenko
doaj  

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

Digital model for predicting the risk of developing acute decompensated heart failure

Рациональная фармакотерапия в кардиологии
Aim. Development and external validation of a risk prediction model for acute decompensated heart failure (ADHF) in patients with low left ventricular ejection fraction.Material and methods.
N. B. Lebedeva, A. P. Egle, Yu. A. Argunova, O. L. Barbarash   +3 more
doaj   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source