Results 101 to 110 of about 3,639,746 (361)

EPI Update, September 2, 2011 [PDF]

open access: yes, 2011
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]

open access: yes, 2010
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana   +6 more
core   +1 more source

A Reconsideration of Acute Beryllium Disease

open access: yesEnvironmental Health Perspectives, 2009
Although chronic beryllium disease (CBD) is clearly an immune-mediated granulomatous reaction to beryllium, acute beryllium disease (ABD) is commonly considered an irritative chemical phenomenon related to high exposures. Given reported new cases of ABD and projected increased demand for beryllium, we aimed to reevaluate the patho physiologic ...
Kristin J. Cummings   +3 more
openaire   +3 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Parametric analysis of the transmission dynamics during indigenous aggregated outbreaks caused by five SARS-CoV-2 strains in Nanjing, China

open access: yesFrontiers in Public Health
BackgroundSARS-CoV-2 strains have been of great concern due to their high infectivity and antibody evasion.MethodsIn this study, data were collected on indigenous aggregated outbreaks in Nanjing from January 2020 to December 2022, caused by five strains ...
Tao Ma   +9 more
doaj   +1 more source

ACUTE TONSILLAR DISEASES AND THEIR SEQUELAE. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1900
The tonsils belong to the hemopoietic system, and are germinating centers for the leucocytes. Their period of greatest activity is in childhood and youth, when all the lymphatic organs are especially active, and when the thymus gland is disappearing.1 Surrounding the tonsillar follicles are plexuses of lymphatics, and in the tissues of the tonsils ...
openaire   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]

open access: yes, 2005
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J.   +3 more
core  

Sphingosine-1-phosphate promotes the persistence of activated CD4 T cells in inflamed sites [PDF]

open access: yes, 2017
Inflammation can be protective or pathogenic depending on context and timeframe. Acute inflammation, including the accumulation of CD4 T cells, accompanies protective immune responses to pathogens, but the presence of activated CD4 T cells at sites of ...
Ammit   +46 more
core   +3 more sources

Studies on acute disease models

open access: yesKidney International, 1982
Investigations utilizing the isolated perfused tubule technique have greatly enhanced our understanding of normal renal physiology. Recently, however, these methods have been applied to disease models to provide information on the kidney's response to acute and chronic pathologic conditions.
openaire   +3 more sources

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