Results 81 to 90 of about 8,378,867 (316)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Different infective forms trigger distinct immune response in experimental Chagas disease. [PDF]
, 2012 Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface.
Olindo Assis Martins-Filho +35 more
core +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Clinical value of chest pain presentation and prodromes on the assessment of cardiovascular disease: a cohort study. [PDF]
, 2015 OBJECTIVES: The recognition of coronary artery disease (CAD) among patients who report chest pain remains difficult in primary care. This study investigates the association between chest pain (specified, unspecified or musculoskeletal) and prodromes ...
Robson, J +9 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Zhongguo gonggong weishengObjectiveTo assess the status and determinants of knowledge of prevention and treatment of infectious diarrhea among parents of children aged ≤5 years with diarrhea to provide evidence for the development of targeted health intervention strategies ...
Yuanfang SUN +9 more
doaj +1 more source
DIET IN ACUTE INFECTIOUS DISEASES [PDF]
Journal of the American Medical Association, 1911 Feeding the sick is both a science and an art; a science in so far as it takes cognizance of the great laws of supply and demand in a physiologic sense; an art in so far as it affects the application of these laws to the individual. All matter is endowed with a certain amount of energy, which manifests itself differently, under different conditions ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review [PDF]
, 2009 Exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the natural history of this prevalent and devastating condition. This review provides a concise, state of the art summary on prevention and management of exacerbations.
Hurst, JR +5 more
core +2 more sources
Frontiers in Public HealthBackgroundIt is important to figure out the immunity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) reinfection to understand the response of humans to viruses. A serological survey for previously infected populations in Jiangsu Province
Jinjin Chu +18 more
doaj +1 more source