Results 81 to 90 of about 2,343,040 (267)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Evaluation of protective efficacy of an inactivated Japanese encephalitis virus genotype Ⅴ strain in mice

npj Vaccines
The detection of Japanese encephalitis virus (JEV) genotype V (GV) in humans in Korea in 2015 has raised concerns regarding its potential public health impact.
Jung-Min Lee, Seong-Ryeol Kim, Jungsang Ryou, Jang-Hoon Choi, Sang-Mu Shim   +4 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

Spatial extent of dysbiosis in the branching coral Pocillopora damicornis during an acute disease outbreak. [PDF]

Sci Rep, 2023
Greene A, Moriarty T, Leggatt W, Ainsworth TD, Donahue MJ, Raymundo L.   +5 more
europepmc   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science
Colorectal cancer (CRC) progression is regulated by an immunosuppressive tumor microenvironment, but the epigenetic mechanisms governing this milieu remain unclear. This study identifies the histone demethylase KDM6B as a key regulator of myeloid‐derived
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
doaj   +1 more source

Evolution and the potential for human-to-human transmission of severe fever with thrombocytopenia syndrome virus in low transmission settings in China

New Microbes and New Infections
Objective: Severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease with substantial mortality, was first reported in China in 2009 and subsequently became endemic to South Korea, Japan, Vietnam, and the United Arab Emirates ...
Yin Wang, Yao Huang, Jie Liang, Qiumei Li, Liguo Zhu, Shuyi Liang, Zhifeng Li, Chaojie Xu, Jianli Hu, Yun Gu, Yuyang Ge, Xiuling Zhang, Zhengya Wei, Luojing Zhou, Guangyu Lu   +14 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

The latency time of SARS-CoV- 2 Delta variant in infection- and vaccine-naive individuals from Vietnam

BMC Infectious Diseases
Background The latency time (from infection to infectiousness) guides the choice of measures required to control an infectious disease. Estimates of the SARS-CoV- 2 latency time are sparse due to lack of appropriate and representative data.
Vera H. Arntzen, Manh Nguyen Duc, Marta Fiocco, Lan Truong Thi Thanh, Tam Nguyen Hoai Thao, Buu Mai Thanh, Tu-Anh Nguyen, Nhat Le Thanh Hoang, Marc Choisy, Lam Phung Khanh, Nga Le Hong, Ronald B. Geskus   +11 more
doaj   +1 more source

Acute disease induced cognitive dysfunction in older patients - an unrecognized syndrome. [PDF]

BMC Geriatr, 2022
Wirth R, Klimek CN, Lueg G, Pourhassan M, Danielzik LM, Krüger C, Trampisch US.   +6 more
europepmc   +1 more source