Results 101 to 110 of about 3,913,833 (314)
EPI Update, September 2, 2011 [PDF]
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Comorbidities in aging patients with sickle cell disease. [PDF]
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Objectives: Avian influenza (AI) H5N6 has replaced H5N1 as the predominant strain, and the increasing number of cases and complex recombination patterns pose significant threats to human health.
Fuyin Bi +8 more
doaj +1 more source
EPI Update, May 29, 2009 [PDF]
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
EPI Update, August 31, 2012 [PDF]
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
core
Diarrhoea, acute respiratory infection, and fever among children in the Democratic Republic of Congo [PDF]
Several years of war have created a humanitarian crisis in the Democratic Republic of Congo (DRC) with extensive disruption of civil society, the economy and provision of basic services including health care.
Ahiadeke +30 more
core +1 more source

