Results 71 to 80 of about 3,913,833 (314)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Transiently produced IgGs enable universal SARS-CoV-2 diagnosis and differentiation recent from past infections

Microbiology Spectrum
Early diagnosis and differentiating infected from vaccinated animals (DIVA) are the milestone in mitigation, control, and eradication of virus. However, the continuous evolution of new virus strains has hindered the success of many classical techniques ...
Chuchu Li, Jingzhi Li, Chen Dong, Qian Zhen, Xiaoyu Li, Lan Yang, Jingjing Cao, Xiaoxiao Kong, Hua Tian, Lu Zhou, Fengcai Zhu, Hongwei Ma, Liguo Zhu   +12 more
doaj   +1 more source

EPI Update, July 20, 2007 [PDF]

, 2007
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

EPI Update, April 3, 2009 [PDF]

, 2009
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Neutralizing Antibody-Mediated Protection from Prior Delta Variant Infection Against Omicron BA.5 Sub-Lineage Reinfection One Year Later: A Prospective Cohort Study

Vaccines
Background: Previous SARS-CoV-2 infection provides some level of protection against reinfection. However, few studies have evaluated the neutralizing antibody (NAb) response after Delta variant infection and its ability to prevent reinfection with ...
Shihan Zhang, Yin Wang, Guo Xu, Chen Dong, Hua Tian, Chuchu Li, Xiaoxiao Kong, Jiefu Peng, Haodi Huang, Aidibai Simayi, Fengcai Zhu, Jianli Hu, Ke Xu, Changjun Bao, Hui Jin, Liguo Zhu   +15 more
doaj   +1 more source

EPI Update, August 6, 2010 [PDF]

, 2010
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Sarcoidosis Presenting as Acute Respiratory Distress Syndrome. [PDF]

, 2018
Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory ...
Chan, Vincent, Lashari, Bilal, Raza, Ahmad, Ward, William   +3 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source