Results 131 to 140 of about 14,159,590 (434)
Epidemiology of coronary heart disease and acute coronary syndrome.
The aim of this review is to summarize the incidence, prevalence, trend in mortality, and general prognosis of coronary heart disease (CHD) and a related condition, acute coronary syndrome (ACS).
F. Sanchis-Gomar+3 more
semanticscholar +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Acute graft-versus-host disease
F. Malard+4 more
semanticscholar +2 more sources
BackgroundSARS-CoV-2 strains have been of great concern due to their high infectivity and antibody evasion.MethodsIn this study, data were collected on indigenous aggregated outbreaks in Nanjing from January 2020 to December 2022, caused by five strains ...
Tao Ma+9 more
doaj +1 more source
ACUTE TONSILLAR DISEASES AND THEIR SEQUELAE. [PDF]
The tonsils belong to the hemopoietic system, and are germinating centers for the leucocytes. Their period of greatest activity is in childhood and youth, when all the lymphatic organs are especially active, and when the thymus gland is disappearing.1 Surrounding the tonsillar follicles are plexuses of lymphatics, and in the tissues of the tonsils ...
openaire +2 more sources
Gene Therapy for Acute Diseases
The use of gene transfer systems to study cell function makes it apparent that overexpression of a transgene can restore or improve the function of a protein and positively influence cell function in a predetermined manner for purposes of counterbalancing cellular pathophysiology.
Phillip Factor, Phillip Factor
openaire +3 more sources
EPI Update, April 3, 2009 [PDF]
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
core
Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.
When T cells from a bone marrow donor begin to attack the host within 3 months after hematopoietic-cell transplantation, acute graft-versus-host disease results.
R. Zeiser, B. Blazar
semanticscholar +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source