Results 181 to 190 of about 15,063,784 (383)

ACUTE CHOLECYSTIC DISEASE

open access: yesAnnals of Surgery, 1933
E. Starr Judd   +2 more
openaire   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Ad5-nCoV boosted vaccine and reinfection-induced memory T/B cell responses and humoral immunity to SARS-CoV-2: based on two prospective cohorts

open access: yesEmerging Microbes and Infections
Here, we regularly followed two SARS-CoV-2 infected cohorts to investigate the combined effects of neutralizing antibodies (NAbs) and B and T cell profiles during the convalescent period. Ten infected participants in December 2022 were selected to assess
Aidibai Simayi   +11 more
doaj   +1 more source

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

open access: yesThe Lancet, 2020
Peter J. Richardson   +8 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Scarlet fever and meteorological exposures in Jiangsu, China: a time-stratified case-crossover study

open access: yesBMC Public Health
Background There has been an increasing interest in the association between meteorological risk factors and scarlet fever risk. However, the associations between individual-level exposure to meteorological factors and the scarlet fever risk remain poorly
Kai Wang   +7 more
doaj   +1 more source

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