Is Simple Acute Erysipelas a Local or a Constitutional Disease? [PDF]
John Higginbottom
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DISEASE OF THE PRIMARY MOTOR NEURONES CAUSING THE CLINICAL PICTURE OF ACUTE ANTERIOR POLIOMYELITIS [PDF]
NULL AUTHOR_ID
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Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti+8 more
wiley +1 more source
Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference. [PDF]
Selewski DT+9 more
europepmc +1 more source
The Use of Specific Prophylactic Measures in the Control of Acute Infectious Diseases [PDF]
E.H.R. Harries
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CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee+3 more
wiley +1 more source
A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children: a report from the 26th Acute Disease Quality Initiative (ADQI) conference. [PDF]
Fuhrman DY+8 more
europepmc +1 more source
The Growth of Knowledge of Acute Abdominal Diseases 1800–1900 [PDF]
Zachary Cope
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HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez+5 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source