Results 221 to 230 of about 3,639,746 (361)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Nipah Virus-Associated Neuropathology in African Green Monkeys During Acute Disease and Convalescence. [PDF]

J Infect Dis
Goldin K, Liu Y, Rosenke R, Prado-Smith J, Flagg M, de Wit E.   +5 more
europepmc   +1 more source

Combination of the Focus-Forming Assay and Digital Automated Imaging Analysis for the Detection of Dengue and Zika Viral Loads in Cultures and Acute Disease. [PDF]

J Trop Med, 2022
Bolívar-Marin S, Bosch I, Narváez CF.
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Resistance Training and Nutritional Supplementation in Older Adults with Sarcopenia after Acute Disease: A Feasibility Study. [PDF]

Nutrients
Meza-Valderrama D, Sánchez-Rodríguez D, Peña YC, Ramírez-Fuentes C, Muñoz-Redondo E, Morgado-Pérez A, Ortíz-Agurto N, Finis-Gallardo P, Marco E.   +8 more
europepmc   +1 more source

Cardiac pathology 6 months after hospitalization for COVID-19 and association with the acute disease severity. [PDF]

Am Heart J, 2021
Myhre PL, Heck SL, Skranes JB, Prebensen C, Jonassen CM, Berge T, Mecinaj A, Melles W, Einvik G, Ingul CB, Tveit A, Berdal JE, Røsjø H, Lyngbakken MN, Omland T.   +14 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Decrease in Hemoglobin Levels during Acute Attacks in Patients with Idiopathic Recurrent Pericarditis: A Model of Anemia in Acute Disease. [PDF]

J Clin Med
Casarin F, Mascolo R, Motta I, Wu MA, Bizzi E, Pedroli A, Dieguez G, Iacomelli G, Serati L, Duca L, Maestroni S, Tombetti E, Cappellini MD, Brucato A.   +13 more
europepmc   +1 more source

Kambô-Induced Systemic Inflammatory Response: A Case Report of Acute Disease Progression of Cholangiocarcinoma. [PDF]

Integr Cancer Ther, 2021
Peleg Hasson S, Shachar E, Kessner R, Shpigel S, Wolf I.   +4 more
europepmc   +1 more source

Clinical Notes on a Case of Acute Mania; bearing upon the Effect of Acute Intercurrent Disease as it affects the Mental State [PDF]

, 1904
Lewis C. Bruce
openalex   +1 more source