Results 41 to 50 of about 15,063,784 (383)

Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

Frontiers in Pharmacology, 2021
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of ...
Caixia Li, Lihua Cui, Lanqiu Zhang, Lei Yang, Yuzhen Zhuo, Jialin Cui, Naiqiang Cui, Shukun Zhang   +7 more
doaj   +1 more source

Could SARS-CoV-2-Induced Hyperinflammation Magnify the Severity of Coronavirus Disease (CoViD-19) Leading to Acute Respiratory Distress Syndrome?

Frontiers in Immunology, 2020
Citation: Girija ASS, Shankar EM and Larsson M (2020) Could SARS-CoV-2-Induced Hyperinflammation Magnify the Severity of Coronavirus Disease (CoViD-19) Leading to Acute Respiratory Distress Syndrome? Front. Immunol. 11:1206. doi: 10.3389/fimmu.2020.01206
L. F. V. Dyk, A. Girija, E. Shankar, M. Larsson   +3 more
semanticscholar   +1 more source

Prognostic value of serum oncomarkers for patients hospitalized with acute exacerbation of interstitial lung disease

Therapeutic Advances in Respiratory Disease
Background: Different types of inflammatory processes and fibrosis have been implicated in the pathogenesis of interstitial lung disease (ILD), a heterogeneous, diffuse, parenchymal lung disease.
Cuirong Ba, Chunguo Jiang, Huijuan Wang, Xuhua Shi, Jiawei Jin, Qiuhong Fang   +5 more
semanticscholar   +1 more source

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China.

JAMA Neurology, 2020
Importance The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, is serious and has the potential to become an epidemic worldwide. Several studies have described typical clinical manifestations including fever, cough, diarrhea, and fatigue.
L. Mao, Huijuan Jin, Mengdie Wang, Yu Hu, Shengcai Chen, Quanwei He, Jiang Chang, Can-dong Hong, Yifan Zhou, David Wang, Xiao-ping Miao, Ya-nan Li, Bo Hu   +12 more
semanticscholar   +1 more source

Changes of influenza vaccination rate and associated influencing factors after the COVID-19 pandemic in Shanghai, China

Human Vaccines & Immunotherapeutics
The vaccination rate for seasonal influenza remains low in most regions of China. It is essential to understand the factors that associated with the low influenza vaccination rate in various populations after the COVID-19 pandemic.
Geyang Sun, Li Zhang, Ye Qiu, Yilin Jia, Yuanping Wang, Hongmei Xu, Anran Zhang, Lipeng Hao, Weiping Zhu, Chuchu Ye   +9 more
doaj   +1 more source

A new coronavirus associated with human respiratory disease in China

Nature, 2020
Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health1–3.
Fan Wu, Su Zhao, Bin Yu, Yan-Mei Chen, Wen Wang, Zhigang Song, Y. Hu, Zhaowu Tao, Jun-hua Tian, Yuan-Yuan Pei, Mingli Yuan, Yuling Zhang, Fahui Dai, Yi Liu, Qimin Wang, Jiao-Jiao Zheng, Lin Xu, E. Holmes, Yong‐Zhen Zhang   +18 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Long-Term Kinetics of SARS-CoV-2 Antibodies and Impact of Inactivated Vaccine on SARS-CoV-2 Antibodies Based on a COVID-19 Patients Cohort

Frontiers in Immunology, 2022
BackgroundUnderstanding the long-term kinetic characteristics of SARS-CoV-2 antibodies and the impact of inactivated vaccines on SARS-CoV-2 antibodies in convalescent patients can provide information for developing and improving vaccination strategies in
Shihan Zhang, Shihan Zhang, Ke Xu, Chuchu Li, Lu Zhou, Xiaoxiao Kong, Jiefu Peng, Fengcai Zhu, Fengcai Zhu, Fengcai Zhu, Changjun Bao, Hui Jin, Hui Jin, Qiang Gao, Xing Zhao, Liguo Zhu, Liguo Zhu, Liguo Zhu, Liguo Zhu   +18 more
doaj   +1 more source

Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

Glia, 2016
Microglial clusters with C3d deposits are observed in the periplaque of multiple sclerosis (MS) brains and were proposed as early stage of lesion formation. As such they should appear in the brain of MS donors with acute disease but thus far this has not
I. Michailidou, Daphne M. P. Naessens, S. Hametner, Willemijn Guldenaar, Evert-Jan Kooi, J. Geurts, F. Baas, H. Lassmann, V. Ramaglia   +8 more
semanticscholar   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source