Results 51 to 60 of about 14,622 (186)

Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD

Annals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2460-2469, December 2025.
ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz, Carolin Otto, Klemens Ruprecht, Susanna Asseyer, Hannes Ole Tiedt, Christian Meisel, Judith Bellmann‐Strobl, Friedemann Paul, Patrick Schindler   +8 more
wiley   +1 more source

Myasthenia Gravis in a Child With Schimke Immuno‐Osseous Dysplasia: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT We report a rare association between Schimke immune‐osseous dysplasia and myasthenia gravis. Clinicians should be aware of potential autoimmune neuromuscular complications in SIOD, as early recognition and tailored immunosuppression may improve prognosis.
Mohamed S. Al Riyami, Intisar Al Alawi, Maisa Al Riyami, Badria Al Gaithi, Suliman Al Saidi, Ibtisam Al Shuaili, Naifain Al Kalbani, Nabil Al Maki   +7 more
wiley   +1 more source

Acute Disseminated Encephalomyelitis: A case series and review of literatures

Journal of Pediatrics Review, 2013
Acute disseminated encephalomyelitis is a rare immune mediated and demyelinating disease of the central nervous system that usually affects children. It is a monophasic disorder related with multifocal neurologic symptoms.
Mohammad Sadegh Rezai, Mehrdad Taghipour, Fariborz Azizi, Ali Abbaskhanian   +3 more
doaj  

Dysbiosis and Therapeutic Modulation of the Gut Microbiota in Multiple Sclerosis: A Narrative Review

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Multiple sclerosis (MS) is a persistent autoimmune disease that affects the central nervous system. The etiology of MS is complex, involving a variety of genetic and environmental factors. Mounting evidence suggests that dysbiosis significantly impacts the progression of MS mainly through its direct effects upon the immune ...
Mojtaba Memariani, Hamed Memariani
wiley   +1 more source

Cerebellar Mutism in Acute Disseminated Encephalomyelitis

Pediatric Neurology Briefs, 2010
Researchers at a pediatric multiple sclerosis clinic, the Neurological Institute, Buffalo General Hospital, New York, report six (32%) of 19 patients diagnosed with acute disseminated encephalomyelitis (2005-9) who had protracted speech and language ...
J Gordon Millichap
doaj   +1 more source

Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations

MedComm, Volume 6, Issue 12, December 2025.
Along with organismal aging or pathogenic processes especially tumor, multiple immune cell types exhibit those well‐established hallmarks of cellular senescent phenotype, mainly characterized by irreversible cell cycle arrest, metabolic disorder, and over production of SASP.
Ninghan Gong, Xiting Pan, Yusi Deng, Jiajia Che, Junhao Bao, Mengqi Wang, Chuan Xu, Xiaowei Liu, Ying Shi   +8 more
wiley   +1 more source

The Value of Oligoclonal Bands in Multiple Sclerosis Compared to Other Neurological Disorders: A Retrospective Data Analysis From an Austrian Tertiary Center

European Journal of Neurology, Volume 32, Issue 12, December 2025.
ABSTRACT Background Cerebrospinal fluid (CSF) analysis is key to diagnosing multiple sclerosis (MS). In particular, the presence of CSF‐specific oligoclonal bands (OCB) is examined alongside differential diagnostic aspects. This study aims to investigate the diagnostic value of OCB in MS compared to other neurological disorders.
Tobias Monschein, Benjamin Scheicher, Markus Ponleitner, Nik Krajnc, Fabian Föttinger, Tobias Zrzavy, Paulus Rommer, Barbara Kornek, Gabriel Bsteh, Thomas Perkmann, Thomas Berger, Fritz Leutmezer   +11 more
wiley   +1 more source

Acute disseminated encephalomyelitis (ADEM), Report A Rare Case of Refractory form to treatment (PP-03) [PDF]

Neurology Letters, 2023
Introduction: Acute disseminated encephalomyelitis (ADEM) is a rare disease of central nervous system with myriads of presentation. We report a case with atypical feature and partial response to treatment.
Mohammad Amin Najafi
doaj  

Chimeric Antigen Receptor T‐Cell Therapy and Autoimmune Diseases in the Nervous System

Immunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.
ABSTRACT Introduction Chimeric antigen receptor T‐cell (CAR‐T) therapy, a revolutionary immunotherapy originally developed for hematologic malignancies, has recently gained attention for its potential in treating autoimmune diseases. Increasing evidence suggests that CAR‐T cells can precisely target pathogenic immune populations, offering durable ...
Shun‐yu Yao, Miao‐qiao Du, Huan Yang, Qiu‐ming Zeng, Hao Zhou, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Lan‐xin Lin, Xu‐hui Kang, Dai‐yi Jiang, Yong Peng   +11 more
wiley   +1 more source

An Interesting Case Of Acute Disseminated Encephalomyelitis

Online Journal of Health & Allied Sciences, 2008
Acute disseminated encephalomyelitis (ADEM) is an uncommon inflammatory demyelinating disease of the central nervous system. The disease typically occurs after infections or vaccinations.
Satish Kumar, Mohit Sharma, Ashok Sharma, Rajiv Raina   +3 more
doaj