Results 51 to 60 of about 1,625,326 (183)

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Diagnostic Challenges in a Nine-year-old Boy with ADEM and Longitudinal Extensive Transverse Myelitis

Journal of Pediatric Emergency and Intensive Care Medicine
Acute disseminated encephalomyelitis (ADEM), or postinfectious encephalomyelitis, is a demyelinating central nervous system disease that typically presents with multifocal neurologic symptoms and encephalopathy.
Emine Akkuzu, Mutlu Uysal Yazıcı, Ebru Azapağası, Tuğba Hirfanoğlu, Betül Derinkuyu, Hasan Tezer   +5 more
doaj   +1 more source

ADEM: Age at Onset and Neuropsychological Outcome

Pediatric Neurology Briefs, 2004
The influence of age at onset of acute disseminated encephalomyelitis (ADEM) on cognitive, educational, and social functioning was evaluated in 19 children (10 < 5 years of age) admitted to the Royal Children’s Hospital, Melbourne, Australia.
J Gordon Millichap
doaj   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Coronavirus and ADEM

Pediatric Neurology Briefs, 2004
A boy aged 15 years with acute disseminated encephalomyelitis (ADEM) found to have human coronavirus (HCoV) in the cerebrospinal fluid (CSF) and nasopharynx is reported from the Children’s Hospital of Buffalo, SUNY at Buffalo, NY.
J Gordon Millichap
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Isolated palatal weakness without optic neuritis as the presenting manifestation of multiple sclerosis and its diagnostic dilemma with acute disseminated encephalomyelitis in a young boy

Avicenna Journal of Medicine, 2017
We present a case of a young boy who at initial presentation was diagnosed as acute disseminated encephalomyelitis (ADEM) but subsequently on follow-up was diagnosed as multiple sclerosis (MS). Differentiating ADEM from MS in their first presentation can
Virti D Shah, Sumeet Prakash Mirgh, Nirmal Surya   +2 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Post-traumatic acute disseminated encephalomyelitis [PDF]

, 2012
A 23-year-old black African male fell and bumped his head from a tackle while playing soccer. He subsequently became blind from optic neuritis. An MRI of the brain showed white-matter changes suggestive of acute disseminated encephalomyelitis (ADEM).
Legwara, Patrick, Matlala, Baile, Sebiloane, Sidney, Patel, Jeshal, Magazi, Dali, Wynand-Ndlovu, Lezanne   +5 more
core   +1 more source

Pattern and Outcome of Acute Disseminated Encephalomyelitis (ADEM) [PDF]

The Egyptian Journal of Hospital Medicine, 2019
Background: Acute disseminated encephalomyelitis (ADEM) is an immune disease marked by widespread of inflammation in the brain and spinal cord. ADEM typically damages myelin, causing destruction of white matter. It often occurs following a viral infection or vaccination. Its symptoms are similar to multiple sclerosis (MS) and are considered part of the 
Mohsen Taha Elkeiy, Kamel Suliman Hamad, Al Hassan Mustafa Zahran, Haytham Muhammad Nafady, Noman Al Basiouny Gouda   +4 more
openaire   +1 more source