Results 121 to 130 of about 12,566,425 (256)

Effect of acute exercise on postprandial lipemia and endothelial function in men with peripheral arterial disease [PDF]

open access: yes, 2012
Introduction: Postprandial lipidemia (PPL), defined as an increase in plasma levels of triglyceride-rich lipoproteins following the consumption of a high fat meal (HFM) is associated with endothelial dysfunction. Acute exercise reduces PPL and maintains
O'Hara, Kevin, O\u27Hara, Kevin
core   +2 more sources

Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway

open access: yes, 2018
Mohammad Hassan Hodroj, Achraf Jardaly, Sarah Abi Raad, Annalise Zouein, Sandra Rizk Department of Natural Sciences, Lebanese American University, Beirut, Lebanon Background: Topotecan (TP) is an anticancer drug acting as topoisomerase I inhibitor that ...
Abi Raad S   +4 more
core  

Violent behavior in acute psychiatric inpatient facilities: A national survey in italy

open access: yes, 2009
Violence committed by acute psychiatric inpatients represents an important and challenging problem in clinical practice. The aim of this study is to evaluate the prevalence and characteristics of violent and hostile behavior and to identify predictors of
DE GIROLAMO G. for the PROGRES Acute Group   +6 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The role of CAT in evaluating the response to treatment of patients with AECOPD

open access: yesInternational Journal of COPD, 2018
Aiyuan Zhou,1–3 Zijing Zhou,1–3 Yating Peng,1–3 Yiyang Zhao,1–3 Jiaxi Duan,1–3 Ping Chen1–3 1Department of Respiratory Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China ...
Zhou A   +5 more
doaj  

Inhibitory effect of the Kampo medicinal formula Yokukansan on acute stress-induced defecation in rats

open access: yes, 2018
Yasuaki Kanada, Ayami Katayama, Hideshi Ikemoto, Kana Takahashi, Mana Tsukada, Akio Nakamura, Shogo Ishino, Tadashi Hisamitsu, Masataka Sunagawa Department of Physiology, School of Medicine, Showa University, Shinagawa-ku, Tokyo, Japan Objectives ...
Kanada Y   +8 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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