Results 191 to 200 of about 12,566,425 (256)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Acute effect of school-based active breaks on physical activity level and on-task classroom behavior in primary schoolchildren. [PDF]

Front Public Health
Reyes-Amigo T, Grao-Cruces A, Sanchez-Oliva D, Garcia-Hermoso A, Reyes-Molina D, Yañez-Sepúlveda R, Olivares-Arancibia J, Hurtado-Almonácid J, Páez-Herrera J, Salinas-Gallardo G, Mendoza E, Ovalle-Fernández C, Sepúlveda-Figueroa F, Ibarra-Mora J.   +13 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Acute effect of whole-body vibration on hand grip strength, muscular activity, and upper limb function in young females with smartphone addiction: a randomized controlled trial. [PDF]

Front Med (Lausanne)
Allam NM, Alkhaldi RA, Alshammari WZ, Salama MEM, Abed SY, Ibraheem KM, Ebrahim HA, El-Sherbiny M, Salem HE, Abdelrahman MMA, Eladl HM.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Acute Effect of High Fat Intake on Urinary Acidification Parameters. [PDF]

Kidney Int Rep
Zomorodian A, Li X, Poindexter J, Maalouf NM, Moe OW, Sakhaee K.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The acute effect of night work-related circadian misalignment on headache episodes: Results from the 1001 nights-cohort. [PDF]

Headache
Harmsen R, Hansen JM, Matre D, Arup AESF, Garde AH, Nabe-Nielsen K.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Acute Effect of Dryland Maximum Strength Training Session on Sport-Specific Performance Tests in Female Water Polo Players. [PDF]

Sports (Basel)
Malliaros I, Arsoniadis GG, Botonis PG, Terzis G, Platanou T, Toubekis AG.   +5 more
europepmc   +1 more source