Results 141 to 150 of about 1,981,808 (273)
Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care
Pediatric Investigation, EarlyView.This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley +1 more source
The Experience of Acute Illness: Whose Experience?
, 1986 The experience of acute illness can be viewed from the perspective of the nurse in terms of the knowledge and skill she has gained (based on personal contact with and observation of persons in this situation) or from the perspective of persons who meet ...
Bronwyn Paterson
core
Acta Paediatrica, EarlyView.ABSTRACT Aim To provide an update paper on evidence of adverse events of concern following immunization (AEFI) with pertussis vaccines, focusing primarily on acellular (aP) vaccines. Methods Evidence was synthesised from epidemiological studies, systematic reviews over recent decades, expert interpretations in reviews from relevant research teams and ...
Lennart Nilsson, Jann Storsaeter
wiley +1 more source
, 2018 Characteristics of 96 enrolled patients hospitalized with acute febrile illness compatible with leptospirosis–Salvador, Brazil 2012.
Albert I. Ko (90448) +9 more
core +1 more source
British Journal of Haematology, EarlyView.Summary Glofitamab was investigated with obinutuzumab/rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (G/R‐CHOP) in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (B‐NHL) who had ≥1 prior obinutuzumab/rituximab‐containing therapy (NCT03467373). The primary end‐point was to determine the optimal biological dose of
William Townsend +16 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary The Hodgkin lymphoma treatment in the elderly (eHL) is a challenge due to a narrow therapeutic window between therapy effectiveness and toxicity. Both bendamustine (Be) and brentuximab vedotin (BV) are well‐tolerated, effective drugs in relapsing HL, but no data exist on Be‐BV frontline treatment in eHL.
Andrea Gallamini +15 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Inborn errors of immunity in children with neuroinflammation
Developmental Medicine &Child Neurology, EarlyView.Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
, 2018 * Undifferentiated fever includes any other febrile illness consistent with acute clinical leptospirosis not elsewhere categorized. EBV = Epstein-Barr virus. HUS/TTP = hemolytic uremic syndrome/thrombotic thrombocytopenic purpura.
Albert I. Ko (90448) +9 more
core +1 more source
Early tocilizumab and outcomes in acute necrotizing encephalopathy
Developmental Medicine &Child Neurology, EarlyView.Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han +14 more
wiley +1 more source