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Dengue, caused by four closely related viruses, is a growing global public health concern, with outbreaks capable of overwhelming health-care systems and disrupting economies. Dengue is endemic in more than 100 countries across tropical and subtropical regions worldwide, and the expanding range of the mosquito vector, affected in part by climate change,
Billick, Maxime J., Bogoch, Isaac I.
semanticscholar +12 more sources
SUMMARY Dengue is an acute mosquito-borne viral disease that is highly prevalent throughout the tropical world. The geographic footprint of the four dengue viruses (DENV-1 to -4) that cause this disease and their Aedes mosquito vector is expanding, extending into North ...
Shirin Kalimuddin +3 more
openaire +4 more sources
Dengue and Dengue Hemorrhagic Fever [PDF]
SUMMARYDengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue hemorrhagic fever in new geographic regions.
E B, Hayes, D J, Gubler
openaire +5 more sources
Dengue overview: An updated systemic review.
Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and
Muhammad Bilal Khan +8 more
semanticscholar +1 more source
Efficacy of Wolbachia-infected mosquito deployments for the control of dengue
Background: Aedes aegypti mosquitoes infected with Wolbachia pipientis (wMel strain) have reduced potential to transmit dengue viruses. Methods: We conducted a cluster randomised trial of deployments of wMel-infected Ae.
A. Utarini +23 more
semanticscholar +1 more source
Dengue Virus: Epidemiology, Biology and Disease Aetiology.
Dengue is a vector-borne viral disease, caused by the Flavivirus, Dengue virus (DENV). About 400 million cases and 22000 deaths occur due to dengue throughout the world each year.
Sudipta Roy, S. Bhattacharjee
semanticscholar +1 more source
Is new dengue vaccine efficacy data a relief or cause for concern?
Dengue is a major global public health problem requiring a safe and efficacious vaccine as the foundation of a comprehensive countermeasure strategy. Despite decades of attempts, the world has a single dengue vaccine licensed in numerous countries, but ...
Stephen J. Thomas
semanticscholar +1 more source
Dengue: Update on Clinically Relevant Therapeutic Strategies and Vaccines
Dengue viruses (DENV) continue to circulate worldwide, resulting in a significant burden on human health. There are four antigenically distinct serotypes of DENV, an infection of which could result in a potentially life-threatening disease.
Monica Palanichamy Kala +2 more
semanticscholar +1 more source
Dengue infection: Global importance, immunopathology and management.
Dengue is an arboviral infection that is hyperendemic in tropical and subtropical climates. Clinical manifestations of dengue can range from asymptomatic infection to severe infection with multi-organ failure.
S. Kularatne, Chamara Dalugama
semanticscholar +1 more source
Background Dengue is one of the most common vector-borne diseases globally, however, its burden is poorly quantified. Hence, we aimed to report the dengue burden in 195 countries and territories between 1990 and 2017, using data from the Global Burden of
Zhilin Zeng +4 more
semanticscholar +1 more source

