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Dengue Virus Genome Uncoating Requires Ubiquitination [PDF]

open access: yes, 2016
The process of genome release or uncoating after viral entry is one of the least-studied steps in the flavivirus life cycle. Flaviviruses are mainly arthropod-borne viruses, including emerging and reemerging pathogens such as dengue, Zika, and West Nile ...
Byk, Laura Andrea   +5 more
core   +3 more sources

Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]

open access: yes, 2013
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando   +11 more
core   +2 more sources

Theoretical impact of insecticide-impregnated school uniforms on dengue incidence in Thai children. [PDF]

open access: yes, 2013
BACKGROUND: Children carry the main burden of morbidity and mortality caused by dengue. Children spend a considerable amount of their day at school; hence strategies that reduce human-mosquito contact to protect against the day-biting habits of Aedes ...
Amaku, Marcos   +4 more
core   +2 more sources

Multivariate Hierarchical Frameworks for Modelling Delayed Reporting in Count Data [PDF]

open access: yes, 2019
In many fields and applications count data can be subject to delayed reporting. This is where the total count, such as the number of disease cases contracted in a given week, may not be immediately available, instead arriving in parts over time.
Dobson A., Gelman A., R Core Team
core   +3 more sources

Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India

open access: yesBMC Infectious Diseases, 2019
Background Dengue infections have become a huge threat to public health systems in developing countries. Data on seroprevalence and incidence of dengue infections are lacking from rural regions of India.
Paresh S. Shah   +8 more
doaj   +1 more source

SARS-CoV-2 neutralizing antibodies in patients with varying severity of acute COVID-19 illness

open access: yesScientific Reports, 2021
In order to support vaccine development, and to aid convalescent plasma therapy, it would be important to understand the kinetics, timing and persistence of SARS-CoV-2 neutralizing antibodies (NAbs), and their association with clinical disease severity ...
Chandima Jeewandara   +12 more
doaj   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

open access: yes, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien   +6 more
core   +2 more sources

Hemorrhagic encephalopathy in dengue shock syndrome: a case report

open access: yesBrazilian Journal of Infectious Diseases
Dengue fever is the most important arboviral infection in the world, with an estimated 100 million cases per year and 2.5 billion people at risk.
Luiz José de Souza   +7 more
doaj   +1 more source

Identification of Novel Candidate CD8+ T Cell Epitopes of the SARS-CoV2 with Homology to Other Seasonal Coronaviruses

open access: yesViruses, 2021
Cross-reactive T cell immunity to seasonal coronaviruses (HCoVs) may lead to immunopathology or protection during SARS-CoV2 infection. To understand the influence of cross-reactive T cell responses, we used IEDB (Immune epitope database) and NetMHCpan ...
Pradeep Darshana Pushpakumara   +5 more
doaj   +1 more source

The impact of dengue on liver function as evaluated by aminotransferase levels

open access: yesBrazilian Journal of Infectious Diseases
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols.
Luiz José de Souza   +7 more
doaj   +1 more source

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