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Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model) [PDF]

open access: yesPathogens, 2015
Chikungunya virus (CHIKV) is a positive-sense RNA virus transmitted by Aedes mosquitoes. CHIKV is a reemerging Alphavirus that causes acute febrile illness and severe and debilitating polyarthralgia of the peripheral joints.
Rebecca Broeckel   +3 more
doaj   +5 more sources

Infectious Chikungunya Virus (CHIKV) With a Complete Capsid Deletion: A New Approach for a CHIKV Vaccine. [PDF]

open access: yesJournal of Virology, 2019
Currently, there is no licensed vaccine against CHIKV infection. An ideal CHIKV vaccine should generate an optimal balance between efficacy and safety. Live attenuated vaccines that can elicit strong immune responses often involve a trade-off of reduced safety. Here, a novel live attenuated vaccine candidate for CHIKV lacking the entire capsid gene, ΔC-
Han-Qing Ye, Bo Zhang, Zhiming Yuan
exaly   +5 more sources

Calpain-2 protein influences chikungunya virus replication and regulates vimentin rearrangement caused by chikungunya virus infection

open access: yesFrontiers in Microbiology, 2023
Chikungunya fever (CHIF), a vector-borne disease transmitted mainly by Aedes albopictus and Aedes aegypti, is caused by Chikungunya virus (CHIKV) infection. To date, it is estimated that 39% of the world’s population is at risk of infection for living in
Jia Li   +8 more
doaj   +1 more source

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

open access: yesTropical Medicine and Infectious Disease, 2022
Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks.
Marsha Sinditia Santoso   +8 more
doaj   +1 more source

Genome-Wide Approaches to Unravel the Host Factors Involved in Chikungunya Virus Replication

open access: yesFrontiers in Microbiology, 2022
Chikungunya virus (CHIKV), the causative agent of Chikungunya fever (CHIKVF) that is often characterized by fever, headache, rash, and arthralgia, is transmitted to humans by Aedes mosquito bites.
Atsushi Tanaka, Youichi Suzuki
doaj   +1 more source

The research progress of Chikungunya fever

open access: yesFrontiers in Public Health, 2023
Chikungunya fever, an acute infectious disease caused by Chikungunya virus (CHIKV), is transmitted by Aedes aegypti mosquitoes, with fever, rash, and joint pain as the main features.
Li Cai   +8 more
doaj   +1 more source

LABORATORY INVESTIGATION OF CHIKUNGUNYA OUTBREAK IN PERAK FROM 2019 TO 2020

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Chikungunya virus (CHIKV) is a vector-borne virus which is transmitted primarily by Aedes aegypti and Aedes albopictus. A period between 2016 to 2020, chikungunya outbreaks were reported in several Asian countries. In Perak, Malaysia, there was an
Y.Z. Lim
doaj   +1 more source

Equine Polyclonal Antibodies Prevent Acute Chikungunya Virus Infection in Mice

open access: yesViruses, 2023
Chikungunya virus (CHIKV) is a mosquito-transmitted pathogen that causes chikungunya disease (CHIK); the disease is characterized by fever, muscle ache, rash, and arthralgia.
Douglas Barker   +9 more
doaj   +1 more source

Chikungunya Virus: Priority Pathogen or Passing Trend?

open access: yesVaccines, 2023
Chikungunya virus (CHIKV) is considered a priority pathogen and a major threat to global health. While CHIKV infections may be asymptomatic, symptomatic patients can develop chikungunya fever (CHIKF) characterized by severe arthralgia which often ...
Gerardo Montalvo Zurbia-Flores   +2 more
doaj   +1 more source

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.

open access: yesPLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit   +6 more
doaj   +1 more source

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