Results 41 to 50 of about 15,637 (220)

Nonstructural Protein 2 (nsP2) of Chikungunya Virus (CHIKV) Enhances Protective Immunity Mediated by a CHIKV Envelope Protein Expressing DNA Vaccine [PDF]

Viral Immunology, 2013
Chikungunya virus (CHIKV) is an important emerging mosquito-borne alphavirus, indigenous to tropical Africa and Asia. It can cause epidemic fever and acute illness characterized by fever and arthralgias. The epidemic cycle of this infection is similar to dengue and urban yellow fever viral infections.
Bao, Huihui, Ramanathan, Aarti A., Kawalakar, Omkar, Sundaram, Senthil G., Tingey, Colleen, Bian, Charoran B., Muruganandam, Nagarajan, Vijayachari, Paluru, Sardesai, Niranjan Y., Weiner, David B., Ugen, Kenneth E., Muthumani, Karuppiah   +11 more
openaire   +3 more sources

Isolation and diagnosis of Chikungunya virus causing outbreaks in Andhra Pradesh, India [PDF]

Journal of Clinical and Scientific Research, 2013
Background: Chikungunya fever has recently re-emerged in India with a high morbidity. However, the prevalence of chikungunya fever in India has been underreported due to non-availability of specialized kits to confirm the disease in most of the ...
C.V.M. Naresh Kumar, D.V.R. Sai Gopa
doaj  

The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]

, 2016
Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S, Farzan, Michael, Gorman, Matthew J, Hyde, Jennifer L, Poddar, Subhajit   +4 more
core   +2 more sources

Dengue-chikungunya infection in the tertiary care hospital of northern India: Cross-sectional latent class cluster analysis in viral infection

Heliyon, 2023
Cases of dengue and chikungunya fever are escalating all over India. Both viruses share a common vector, the “Aedes” mosquito. Due to similar clinical symptoms, both the dengue (DENV) and chikungunya (CHIKV) virus can circulate as co-infection.
Gaurav Badoni, Puneet Kumar Gupta, Pratima Gupta, Neelam Kaistha, Yogendra Pratap Mathuria, Manju O. Pai, Ravi Kant   +6 more
doaj   +1 more source

Vaccine-induced skewing of T cell responses protects against Chikungunya virus disease [PDF]

, 2019
Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T ...
Ando, Takeshi, Broeckel, Rebecca M, Curiel, David T, DeFilippis, Victor, Denton, Michael, Dmitriev, Igor, Haese, Nicole, Heise, Mark, Kreklywich, Craig N, Messaoudi, Ilhem, Morrison, Thomas E, Powers, John, Smith, Patricia, Streblow, Daniel N   +13 more
core   +3 more sources

Comodulation of Dengue and Chikungunya Virus Infection During a Coinfection Scenario in Human Cell Lines

Frontiers in Cellular and Infection Microbiology, 2022
The Dengue virus (DENV) and Chikungunya virus (CHIKV) are the arboviruses that pose a threat to global public health. Coinfection and antibody-dependent enhancement are major areas of concern during DENV and CHIKV infections, which can alter the clinical
Debjani Taraphdar, Bharati Singh, Bharati Singh, Sabyasachi Pattanayak, Avula Kiran, Avula Kiran, Poornima Kokavalla, Mohd. Faraz Alam, Mohd. Faraz Alam, Gulam Hussain Syed   +9 more
doaj   +1 more source

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]

, 2017
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S, Diamond, Michael S, Fox, Julie M, Hawman, David W, May, Nicholas A, Montgomery, Stephanie A, Moorman, Nathaniel J, Morrison, Thomas E, Sanders, Wes   +8 more
core   +3 more sources

Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection

mBio, 2016
Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook, Anthony J. Lentscher, Paula F. Zamora, Laurie A. Silva, Nicholas A. May, Joshua A. Bauer, Thomas E. Morrison, Terence S. Dermody   +7 more
doaj   +1 more source

Phylogenetic and sequencing analysis of Chikungunya virus (CHIKV) strains from local Pakistani population

Journal of the Pakistan Medical Association, 2021
Objective: The present study aims to outline the genotype of circulating CHIKV strains in Pakistan and their phylogenetic analysis Methods: The study is being conducted at Armed Forces Institute of Pathology after the approval by Institutional Review Board. The study was conducted during the period of Aug 2016 to Sep 2017.
Humaira Aziz, Sawal, Saifullah Khan, Niazi, Eijaz, Ghani, Misbah, Noor   +3 more
openaire   +2 more sources