Results 41 to 50 of about 10,808 (171)
Abstract Climate and environmental changes driven by global economic activities directly affect the physiology of insect vectors, such as Aedes spp., accelerating their development, increasing the number of generations per season and increasing the risk of transmission of aetiological agents. This study aimed to analyse how local climatic variables and
Ana Carolina Felicio‐Alves +4 more
wiley +1 more source
Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation [PDF]
Abstract Chikungunya (CHIKV) and Sindbis (SINV) are arboviruses belonging to the alphavirus genus within the Togaviridae family. They cause frequent epidemics of febrile illness and long-term arthralgic sequelae that affect millions of people each year.
Rathore, A.P.S. +2 more
openaire +2 more sources
Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, there is no licensed vaccine or specific pharmacological treatment.
Paulo Pacheco +14 more
openaire +3 more sources
Reactivity profile of anti-CHIKV mAbs against chikungunya virus-infected cells.
Reactivity profile of anti-CHIKV mAbs against chikungunya virus-infected cells.
Pornsawan Leaungwutiwong (2836934) +12 more
core +1 more source
Abstract Background Babesia is a parasite transmitted by the Ixodes tick and has the potential to be transfusion transmitted. Climate change and changing Ixodes tick distributions in Canada raised questions about the impact of Babesia on the blood supply.
Steven J. Drews +12 more
wiley +1 more source
Development of the Live-Attenuated Chikungunya Virus Vaccine Candidate CHIKV-NoLS
The causal pathogen of chikungunya virus disease, mosquito-transmitted chikungunya virus (CHIKV), has caused significant global epidemics of arthritic disease over the past two decades.
Rao, Shambhavi
core +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
International audienceBACKGROUND: Aedes aegypti and Aedes albopictus are potential vectors of chikungunya virus (CHIKV). The recent CHIKV outbreaks were caused by a new variant characterized by a mutation in the E1 glycoprotein gene (E1-226V) which has ...
Failloux, Anna-Bella +9 more
core +1 more source
ABSTRACT Zika virus (ZIKV), a single‐stranded positive‐sense RNA virus of the Flaviviridae family (Flavivirus genus), causes acute febrile illness and severe congenital anomalies. Serological cross‐reactivity with Dengue virus (DENV) and Chikungunya virus (CHIKV) complicates diagnosis, underscoring the urgency of developing specific point‐of‐care tests
Xiao Cong +14 more
wiley +1 more source
Chikungunya virus (CHIKV) induced disease signs.
A. Pictures of the hind limbs of mock- and CHIKV-infected animals. Chikungunya virus infection induced severe hind limb disease in new born mice. 2–3 day old mice inoculated with 106 PFU (50 ul) of CHIKV by subcutaneous injection in the loose fold of ...
Mohsin Khan (352381) +5 more
core +1 more source

