Results 61 to 70 of about 1,052,896 (217)

Diagnostic Accuracy of Real Time Reverse Transcriptase Polymerase Chain Reaction for Chikungunya Virus Detection: A Systematic Review and Meta‐Analysis

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Chikungunya virus (CHIKV) is an arbovirus that causes an acute febrile illness with intense muscle and joint pain, with the possibility of progressing to a chronic or neurological stage. We conducted a systematic review and meta‐analysis with the aim of evaluating the accuracy of real‐time reverse transcriptase polymerase chain ...
Róger J. Costa   +8 more
wiley   +1 more source

Chikungunya virus and Aedes mosquitoes: saliva is infectious as soon as two days after oral infection.: Salivation and CHIKV [PDF]

open access: yes, 2009
International audienceBACKGROUND: Aedes aegypti and Aedes albopictus are potential vectors of chikungunya virus (CHIKV). The recent CHIKV outbreaks were caused by a new variant characterized by a mutation in the E1 glycoprotein gene (E1-226V) which has ...
Failloux, Anna-Bella   +9 more
core   +1 more source

Chikungunya Virus

open access: yes, 2022
The chikungunya virus (CHIKV) is an RNA virus that is transmitted to humans by Aedes mosquitos commonly found in tropical and subtropical countries. In humans, CHIKV causes an infection with symptoms strikingly like those of the dengue virus and Zika ...

core   +1 more source

HLA class I restriction as a possible driving force for Chikungunya evolution.

open access: yesPLoS ONE, 2010
After two decades of quiescence, epidemic resurgence of Chikungunya fever (CHIKF) was reported in Africa, several islands in the Indian Ocean, South-East Asia and the Pacific causing unprecedented morbidity with some cases of fatality. Early phylogenetic
Joo Chuan Tong   +4 more
doaj   +1 more source

Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate

open access: yesScientific Reports, 2022
Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The development of effective therapeutic strategies could be significantly accelerated with detailed
Marjorie C. L. C. Freire   +16 more
doaj   +1 more source

The Comparative Effectiveness of Vector Control Approaches for Dengue: A Systematic Review and Multilevel Network Meta‐Analysis

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Dengue vector control plays an important role in reducing the burden of dengue infection. Conventional meta‐analysis can only include interventions that can be directly compared. Hence, this study aimed to compare the effectiveness of all interventions for dengue vector control directly and indirectly through a multilevel Bayesian ...
Gary K. K. Low   +5 more
wiley   +1 more source

Mouse Models of Chikungunya Virus

open access: yes, 2016
The majority of medical advances have been made using animals. Studies using mouse models of chikungunya-induced disease have proven invaluable for dissecting the intricate nature of the immune response to this viral infection and identifying potential ...
Stefan Wolf   +11 more
core   +1 more source

Paris Olympics and Paralympics: Insights from nationwide coordination in preparedness, supply chain management and blood inventory

open access: yesVox Sanguinis, EarlyView.
Abstract The Paris 2024 Olympic Games posed a unique challenge due to their scale, associated risks and the need for robust healthcare preparedness. This review outlines the forecasting and anticipatory measures taken by the Etablissement français du sang (EFS) to ensure a resilient blood supply chain throughout the event.
Jean‐Baptiste Thibert   +9 more
wiley   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade   +13 more
wiley   +1 more source

Evolution and immunopathology of chikungunya virus informs therapeutic development [PDF]

open access: yes, 2023
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, is an emerging global threat identified in more than 60 countries across continents. The risk of CHIKV transmission is rising due to increased global interactions, year-round presence of mosquito ...
Anom Bowolaksono   +13 more
core   +1 more source

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