Results 61 to 70 of about 12,242 (218)

Chikungunya virus in Nigeria: A re-emerging threat obscured by diagnostic gaps [PDF]

Chikungunya virus (CHIKV) is re-emerging in Nigeria, but diagnostic and surveillance gaps obscure its true burden. A narrative review of literature and surveillance data (1969–2024) identified consistent serologic and entomologic evidence of CHIKV ...
Adeola Mariam Lateef, Franklyn Ayomide Oluwadare, Mark Musa Hamman, Victor Ibukun Agbajelola   +3 more
core   +1 more source

Genomic epidemiology of Chikungunya virus in Colombia reveals genetic variability of strains and multiple geographic introductions in outbreak, 2014 [PDF]

, 2019
Chikungunya virus (CHIKV) is considered a public health problem due to its rapid spread and high morbidity. This study aimed to determine the genetic diversity and phylogenetic relationships of CHIKVs in Colombia.
Puerta González, Andrés, Peláez Carvajal, Dioselina, Mattar Velilla, Ameth Salim, Hoyos Lopez, Richard Onalbi, Pinzón, Hernando, Muskus, Carlos, Villero Wolf, Yeneiris Karina, Arrieta Bernate, Germán Javier   +7 more
core   +1 more source

Imidazonaphthyridine effects on Chikungunya virus replication: Antiviral activity by dependent and independent of interferon type 1 pathways [PDF]

, 2023
The Chikungunya virus (CHIKV) causes Chikungunya fever, a disease characterized by symptoms such as arthralgia/polyarthralgia. Currently, there are no antivirals approved against CHIKV, emphasizing the need to develop novel therapies.
Sabino-Silva, Robinson, Guevara-Vega, Marco, Grosche, Victória Riquena [UNESP], Torres, Jhoan David Aguillón, Nicolau-Junior, Nilson, Mineo, Tiago Wilson Patriarca, Freire, Marjorie Caroline Liberato Cavalcanti, Jardim, Ana Carolina Gomes [UNESP], Santos, Igor Andrade, Mesquita, Nathalya Cristina de Moraes Roso, Fernandes, Rafaela Sachetto, Ruiz, Uriel Enrique Aquino, Oliva, Glaucius, de Godoy, Andre Schutzer   +13 more
core   +1 more source

Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate

Scientific Reports, 2022
Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The development of effective therapeutic strategies could be significantly accelerated with detailed
Marjorie C. L. C. Freire, Luis G. M. Basso, Luis F. S. Mendes, Nathalya C. M. R. Mesquita, Melina Mottin, Rafaela S. Fernandes, Lucca R. Policastro, Andre S. Godoy, Igor A. Santos, Uriel E. A. Ruiz, Icaro P. Caruso, Bruna K. P. Sousa, Ana C. G. Jardim, Fabio C. L. Almeida, Laura H. V. G. Gil, Carolina H. Andrade, Glaucius Oliva   +16 more
doaj   +1 more source

Diagnostic Accuracy of Real Time Reverse Transcriptase Polymerase Chain Reaction for Chikungunya Virus Detection: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Chikungunya virus (CHIKV) is an arbovirus that causes an acute febrile illness with intense muscle and joint pain, with the possibility of progressing to a chronic or neurological stage. We conducted a systematic review and meta‐analysis with the aim of evaluating the accuracy of real‐time reverse transcriptase polymerase chain ...
Róger J. Costa, Cleyde S. C. Marconi, Gleice K. Jesus, Gabriel O. Franco, Abevailton M. Silva, Maria B. Arriaga, Gúbio C. Soares, Silvia I. Sardi, Eduardo M. Netto   +8 more
wiley   +1 more source

A localized outbreak of Chikungunya virus in Salvador, Bahia, Brazil [PDF]

, 2019
A localized Chikungunya virus (CHIKV; East/Central/South African genotype) outbreak (50 cases, 70% laboratory-confirmed; attack rate: 5.3 confirmed cases/100 people) occurred in a Salvador, Brazil neighborhood, between Apr-Jun/2017.
Mitermayer G Reis (6426872), Laura B Tauro (6426848), Cristiane W Cardoso (6426851), Kitron, Uriel D., Ribeiro, Guilherme S., Nascimento, Leile Cj, Campos, Gubio Soares, Daniela R dos Santos (6426860), Cardoso, Cristiane W., Leile CJ Nascimento (6426857), Reis, Mitermayer G., Gubio S Campos (6426863), Uriel Kitron (119769), Reis, Mitermayer Galvão dos, Kitron, Uriel, Nascimento, Leile C. J., Santos, Daniela Rodrigues dos, Gubio S Campos, Uriel Kitron, Souza, Raquel L., Raquel L Souza, Silvia Sardi, Guilherme S Ribeiro (6426875), Raquel L Souza (6426854), Silvia Sardi (6426866), Tauro, Laura Beatriz, Ribeiro, Guilherme de Sousa, Sardi, Silvia, Cristiane W Cardoso, Laura B Tauro, Olivete B dos Reis (6426869), Santos, Daniela R Dos, Reis, Olivete B Dos, Leile CJ Nascimento, Cardoso, Cristiane Wanderley, Mitermayer G Reis, Olivete B dos Reis, Guilherme S Ribeiro, Reis, Olivete B. dos, Campos, Gubio S., Ferro Sardi, Silvia Natalia, Daniela R dos Santos   +41 more
core   +1 more source

HLA class I restriction as a possible driving force for Chikungunya evolution.

PLoS ONE, 2010
After two decades of quiescence, epidemic resurgence of Chikungunya fever (CHIKF) was reported in Africa, several islands in the Indian Ocean, South-East Asia and the Pacific causing unprecedented morbidity with some cases of fatality. Early phylogenetic
Joo Chuan Tong, Diane Simarmata, Raymond T P Lin, Laurent Rénia, Lisa F P Ng   +4 more
doaj   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source

Information of chikungunya virus (CHIKV) sequences included in the dataset. [PDF]

Information of chikungunya virus (CHIKV) sequences included in the dataset.
Caroline Freitas (15268262), Luiza Benfatti (18156181), Samuel Noah Scamardi (18156172), Bruno Henrique Gonçalves de Aguiar Milhin (18156112), Marcos Tayar Augusto (18156136), Rodrigo Sborghi Rocha (18156163), Karina Rocha Dutra (10377200), Mauricio Lacerda Nogueira (5659780), Natalia Franco Bueno Mistrão (18156139), Emerson Araújo (18156109), Margareth Regina Dibo (5668910), Tayna Manfrin Galvão (18156166), Milene Rocha Ribeiro (5309858), Andreia Francesli Negri (18156106), Andresa Lopes dos Santos (18156133), Thayza Maria Izabel Lopes dos Santos (18156142), Rafael Alves da Silva (18156124), Leonardo Teixeira Cruz (18156184), Pedro Henrique Carrilho Garcia (18156160), Karen Sanmartin Rogovski (18156175), Beatriz de Carvalho Marques (5641796), Cassia Fernanda Estofolete (7586723), Clarita Maria Secco Avilla (18156145), Eliane Aparecida Fávaro (18156169), Nathalia Zini (6715847), Francisco Chiaravalotti-Neto (7292561), Paula Patricia de Freitas Chama (18156187), Renan Luiz Peixoto (18156178), Mânlio Tasso Oliveira (18156190), Tamires Fernanda Pereira dos Santos (18156130), Leonardo Cecílio da Rocha (18156121), Maisa Carla Pereira Parra (10457862), Victor Miranda Hernandes (18156115), Mirella Cezare Gomes (18156157), Gabriela Camilotti Perim (18156154), Aripuanã Sakurada Aranha Watanabe (5309861), Nikos Vasilakis (372511), Gislaine Celestino Dutra da Silva (18156127), Matheus Henrique Tavares Ávila (18156097), Livia Sacchetto (18156103), Hélio Correa Ferraz Júnior (18156151), Scott Cameron Weaver (18156199), Cintia Bittar (4594726), Ana Carolina Bernardes Terzian (18156193), Natalia Morbi Cezarotti (18156100), Victoria Bernardi (18156148), Flora de Andrade Gandolfi (11304375), Cecília Artico Banho (11510308), Tauyne Menegaldo Pinheiro (5309876), Alice de Freitas Versiani (18156196), Leonardo Agopian Trigo (18156118)   +50 more
core   +1 more source

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity [PDF]

, 2018
The arthropod-transmitted chikungunya virus (CHIKV) causes a flu-like disease that is characterized by incapacitating arthralgia. The re-emergence of CHIKV and the continual risk of new epidemics have reignited research in CHIKV pathogenesis.
Ng, Lisa, Yiu-Wing Kam, Couderc, Thérèse, Ruo-Yan Ong, Chow, A, Ong, Ruo-Yan, Kam, Y.-W, Her, Zhisheng, Lisa F. P. Ng, Chia, B.-S, Ng, Lisa F. P., Ng, Lisa FP, Leo, Y.-S, Ong, R.-Y, Chia, Bing-Shao, Kam, Yiu-Wing, Lecuit, Marc, Angela Chow, Laurent Rénia, Rénia, Laurent, Bing-Shao Chia, Couderc, T, Marc Lecuit, Her, Z, Chow, Angela, Lecuit, M, Zhisheng Her, Yee-Sin Leo, Lum, F.-M, Lum, Fok-Moon, Leo, Yee-Sin, Fok-Moon Lum, Rénia, L, Ng, L.F.P, Thérèse Couderc   +34 more
core   +1 more source