Results 71 to 80 of about 1,377,517 (218)

Development of a next-generation chikungunya virus vaccine based on the HydroVax platform.

PLoS Pathogens, 2022
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen responsible for explosive epidemics of febrile illness characterized by debilitating polyarthralgia and the risk of lethal infection among the most severe cases.
Dawn K Slifka, Hans-Peter Raué, Whitney C Weber, Takeshi F Andoh, Craig N Kreklywich, Victor R DeFilippis, Daniel N Streblow, Mark K Slifka, Ian J Amanna   +8 more
doaj   +1 more source

Long‐term stability and reproducibility of frozen plasma control samples for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus by quantitative PCR: Implications for retrospective testing in hemovigilance

Transfusion, Volume 66, Issue 11, Page 2284-2292, November 2026.
Abstract Objective Data on the long‐term stability and reproducibility of nucleic acid amplification testing (NAT) results in frozen stored positive samples (≤−20°C) remain limited. This study evaluated the long‐term performance of frozen virus‐positive samples in quantitative PCR assays and aimed to provide evidence for their analytical reliability in
Benjamin Marx, Annemarie Berger, Niko Kohmer, Marhild Kortenbusch, Sebastian Hoehl, Sandra Ciesek, Holger F. Rabenau   +6 more
wiley   +1 more source

Chikungunya Virus and Zika Virus in Europe

, 2018
Chikungunya fever epidemics display secular, cyclical, and seasonal trends. These epidemics are characterized by explosive outbreaks inter- spersed by periods of disappearance ranging from several years to a few decades.
MARTINA TASSINARI, CLAUDIA CHIESA, SILVIA ZANNOLI, VITTORIO SAMBRI, AGNESE DENICOLÒ, ANNA PIERRO, MANUELA MOROTTI   +6 more
core   +1 more source

Phylogenetic and sequencing analysis of Chikungunya virus (CHIKV) strains from local Pakistani population

Journal of the Pakistan Medical Association, 2021
Objective: The present study aims to outline the genotype of circulating CHIKV strains in Pakistan and their phylogenetic analysis Methods: The study is being conducted at Armed Forces Institute of Pathology after the approval by Institutional Review Board. The study was conducted during the period of Aug 2016 to Sep 2017.
Humaira Aziz, Sawal, Saifullah Khan, Niazi, Eijaz, Ghani, Misbah, Noor   +3 more
openaire   +2 more sources

Advances in CRISPR‐based detection technologies for severe fever with thrombocytopenia syndrome virus (Dabiebanda virus): A mini review

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review summarises the detection methods for severe fever with thrombocytopenia syndrome virus based on CRISPR platforms. (A) CRISPR with fluorescent reporter. (B) CRISPR with lateral flow test strip. (C) CRISPR with DNAzyme. (D) Digital CRISPR. (E) CRISPR with single micro‐ring resonator biosensor. (F) self‐amplifying signal amplification strategy
Junhu Wang, Changqiang Zhu, Jinzhao Chu, Yingqing Mao, Yixin Ge, Haiming Yi, Hongming Wang, Yuexi Li, Yong Qi   +8 more
wiley   +1 more source

Resurgence of chikungunya virus in India: an emerging threat

, 2006
Since December 2005, an outbreak of chikungunya virus (CHIKV) infection has been ongoing in various states of ...
V Lakshmi, S K Saxena, N Mishra, M Singh   +3 more
core   +1 more source

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity [PDF]

, 2018
The arthropod-transmitted chikungunya virus (CHIKV) causes a flu-like disease that is characterized by incapacitating arthralgia. The re-emergence of CHIKV and the continual risk of new epidemics have reignited research in CHIKV pathogenesis.
Ng, Lisa, Yiu-Wing Kam, Couderc, Thérèse, Ruo-Yan Ong, Chow, A, Ong, Ruo-Yan, Kam, Y.-W, Her, Zhisheng, Lisa F. P. Ng, Chia, B.-S, Ng, Lisa F. P., Ng, Lisa FP, Leo, Y.-S, Ong, R.-Y, Chia, Bing-Shao, Kam, Yiu-Wing, Lecuit, Marc, Angela Chow, Laurent Rénia, Rénia, Laurent, Bing-Shao Chia, Couderc, T, Marc Lecuit, Her, Z, Chow, Angela, Lecuit, M, Zhisheng Her, Yee-Sin Leo, Lum, F.-M, Lum, Fok-Moon, Leo, Yee-Sin, Fok-Moon Lum, Rénia, L, Ng, L.F.P, Thérèse Couderc   +34 more
core   +1 more source

Cathepsin B Protease Facilitates Chikungunya Virus Envelope Protein-Mediated Infection Via Endocytosis or Macropinocytosis

Viruses, 2020
Chikungunya virus (CHIKV) is an enveloped virus that enters host cells and transits within the endosomes before starting its replication cycle, the precise mechanism of which is yet to be elucidated.
Mai Izumida, Hideki Hayashi, Atsushi Tanaka, Yoshinao Kubo   +3 more
doaj   +1 more source

Expression of plasmid-based shRNA against the E1 and nsP1 genes effectively silenced Chikungunya virus replication. [PDF]

PLoS ONE, 2012
BACKGROUND: Chikungunya virus (CHIKV) is a re-emerging alphavirus that causes chikungunya fever and persistent arthralgia in humans. Currently, there is no effective vaccine or antiviral against CHIKV infection.
Shirley Lam, Karen Caiyun Chen, Mary Mah-Lee Ng, Justin Jang Hann Chu   +3 more
doaj   +1 more source

Paris Olympics and Paralympics: Insights from nationwide coordination in preparedness, supply chain management and blood inventory

Vox Sanguinis, Volume 121, Issue 10, Page 1525-1535, October 2026.
Abstract The Paris 2024 Olympic Games posed a unique challenge due to their scale, associated risks and the need for robust healthcare preparedness. This review outlines the forecasting and anticipatory measures taken by the Etablissement français du sang (EFS) to ensure a resilient blood supply chain throughout the event.
Jean‐Baptiste Thibert, Hervé Meinrad, Thibaut Bocquet, Marjolaine Jacques, Thierry Baudonet, Pierre Tiberghien, Sabine Cléophax, Syria Laperche, Pierre Gallian, Sophie Le Cam   +9 more
wiley   +1 more source