Results 91 to 100 of about 1,377,517 (218)

A retrospective investigation for the seroprevalence of Chikungunya virus and its co-existence with Dengue virus in Pakistani population, 2014–2015

Scientific Reports
Dengue and Chikungunya are caused by the same vectors, Aedes aegypti and Aedes albopictus. Both mosquitoes are endemic in Pakistan, and various parts of the country experienced outbreaks of Dengue virus over the past decades.
Darakhshan Guhar, Kiran A. Qadir, Fiza Khan, Shafqat F. Rehmani, Sayyada G. Nadeem   +4 more
doaj   +1 more source

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope.

PLoS Neglected Tropical Diseases, 2018
BackgroundChikungunya virus (CHIKV) is the most common alphavirus infecting humans worldwide, causing acute and chronically debilitating arthralgia at a great economic expense.Methodology/principal findingsTo facilitate our study of CHIKV, we generated a
Jing Jin, Michael B Sherman, Daniel Chafets, Nuntana Dinglasan, Kai Lu, Tzong-Hae Lee, Lars-Anders Carlson, Marcus O Muench, Graham Simmons   +8 more
doaj   +1 more source

Eugenol‐Derived Piperazine Mannich Bases as Selective Inhibitors of Mayaro Virus: In Vitro Antiviral Evaluation and Mechanistic Insights

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Arboviruses represent an ongoing global health challenge, particularly in tropical regions where diseases caused by Chikungunya virus (CHIKV) and Mayaro virus (MAYV) continue to emerge. Given the absence of licensed antiviral therapies, the identification of effective small molecules remains critical.
Adriana Cotta Cardoso Reis, Amália Luíza de Sousa da Silva, Camila Portruneli, Augusto Vieira Pontes Silva, Saulo Fehelberg Pinto Braga, Igor Rodrigues Lapa, Thiago Belarmino de Souza, Lucas Lopardi Franco, Diogo Teixeira Carvalho, Geraldo Célio Brandão   +9 more
wiley   +1 more source

Spatial–temporal distribution of chikungunya virus in Brazil: a review on the circulating viral genotypes and Aedes (Stegomyia) albopictus as a potential vector

Frontiers in Public Health
Chikungunya virus (CHIKV) is mainly transmitted by the invasive mosquito Aedes (Stegomyia) aegypti in tropical and subtropical regions worldwide. However, genetic adaptations of the virus to the peri domestic mosquito vector Aedes (Stegomyia) albopictus ...
Maria Eduarda Barreto Resck, Daniel Cardoso Portela Câmara, Flávia Barreto dos Santos, Jefferson Pereira Caldas dos Santos, Barry Wilmer Alto, Nildimar Alves Honório, Nildimar Alves Honório   +6 more
doaj   +1 more source

Chikungunya Virus–Vector Interactions

Viruses, 2014
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes chikungunya fever, a severe, debilitating disease that often produces chronic arthralgia.
Lark L. Coffey, Anna-Bella Failloux, Scott C. Weaver   +2 more
doaj   +1 more source

Molecular and Serological Screening of West Nile and Usutu Virus in Birds and Humans: A Sentinel Study in Finland

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu, Maija T. Suvanto, Sanna Sainmaa, Viktor Olander, Roope Nykänen, Essi M. Korhonen, Anne J. Jääskeläinen   +6 more
wiley   +1 more source

Chikungunya virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans

Cell Reports Medicine
Summary: Chikungunya virus (CHIKV) is a mosquito-borne virus that can cause chronic chikungunya virus disease (CHIKVD), which is characterized by persistent incapacitating arthralgia.
Rimjhim Agarwal, James Chang, Fernanda H. Côrtes, Calvin Ha, John Villalpando, Izabella N. Castillo, Rosa Isela Gálvez, Alba Grifoni, Alessandro Sette, Claudia M. Romero-Vivas, Mark T. Heise, Lakshmanane Premkumar, Andrew K. Falconar, Daniela Weiskopf   +13 more
doaj   +1 more source

Analyzing Upper Extremity Disability From Health‐Related Quality of Life in Chronic Chikungunya: A Biopsychosocial Approach

Journal of Evaluation in Clinical Practice, Volume 32, Issue 6, September 2026.
ABSTRACT Relevance to the Journal Responding to the Journal of Evaluation in Clinical Practice's emphasis on person‐centered care, this study examines how pain, functional capacity and vitality influence lived disability and rehabilitation needs in individuals with chronic chikungunya.
Raildo Oliveira da Silva Filho, Marynara Fabíola Silva Araújo, Andreia Ravinia do Nascimento Oliveira, Maria Eduarda Medeiros da Costa Figueiredo, Dimitri Taurino Guedes, Renata Newman Leite dos Santos Lucena, Leonildo Santos do Nascimento Junior, Thais Marques Lima, Eleazar Marinho de Freitas Lucena   +8 more
wiley   +1 more source

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response

, 2015
International audienceRNA-sensing toll-like receptors (TLRs) mediate innate immunity and regulate anti-viral response. We show here that TLR3 regulates host immunity and the loss of TLR3 aggravates pathology in Chikungunya virus (CHIKV) infection ...
Ng, Lisa, Yiu‐Wing Kam, Wendy WL Lee, Gabriel, Christelle, Chow, A, Kam, Y.-W, Teck‐Hui Teo, Subhra K Biswas, Terk‐Shin Teng, Lulla, Valeria, Andres Merits, Leo, Y.-S, Teo, T.-H, Lulla, Aleksei, Win, M.K, Win, Mar, K, Angela Chow, Valeria Lulla, Laurent Rénia, Andiappan, A.K, Biswas, Subhra,, Yee‐Sin Leo, Biswas, Subhra, K, Marc Lecuit, Christelle Gabriel, Teng, Terk-Shin, Teo, Teck-Hui, Lulla, V, Lecuit, M, Zhisheng Her, Rossella Melchiotti, Gabriel, C, Leo, Yee-Sin, Mar K Win, Fok‐Moon Lum, Tan, Jeslin, Lee, Wendy,, Jeslin JL Tan, Lulla, A, Melchiotti, Rossella, Her, Zhisheng, Lee, W.W.L, Merits, Andres, Aleksei Lulla, Win, Mar,, Lee, Wendy, Wl, Kam, Yiu-Wing, Lecuit, Marc, Andiappan, Anand, K, Teng, T.-S, Lisa FP Ng, Anand K Andiappan, Merits, A, Biswas, S.K, Her, Z, Tan, J.J.L, Chow, Angela, Renia, Laurent, Melchiotti, R, Andiappan, Anand,, Lum, F.-M, Lum, Fok-Moon, Rénia, L, Ng, L.F.P   +63 more
core   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, Volume 66, Issue 9, Page 1786-1799, September 2026.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source