Nonstructural Protein 2 (nsP2) of Chikungunya Virus (CHIKV) Enhances Protective Immunity Mediated by a CHIKV Envelope Protein Expressing DNA Vaccine [PDF]
Viral Immunology, 2013 Chikungunya virus (CHIKV) is an important emerging mosquito-borne alphavirus, indigenous to tropical Africa and Asia. It can cause epidemic fever and acute illness characterized by fever and arthralgias. The epidemic cycle of this infection is similar to dengue and urban yellow fever viral infections.
Bao, Huihui +11 more
openaire +3 more sources
Chikungunya virus and Aedes mosquitoes: saliva is infectious as soon as two days after oral infection.: Salivation and CHIKV [PDF]
, 2009 International audienceBACKGROUND: Aedes aegypti and Aedes albopictus are potential vectors of chikungunya virus (CHIKV). The recent CHIKV outbreaks were caused by a new variant characterized by a mutation in the E1 glycoprotein gene (E1-226V) which has ...
Failloux, Anna-Bella +9 more
core +1 more source
Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection
mBio, 2016 Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook +7 more
doaj +1 more source
Chikungunya virus (CHIKV) induced disease signs. [PDF]
, 2014 A. Pictures of the hind limbs of mock- and CHIKV-infected animals. Chikungunya virus infection induced severe hind limb disease in new born mice. 2–3 day old mice inoculated with 106 PFU (50 ul) of CHIKV by subcutaneous injection in the loose fold of ...
Mohsin Khan (352381) +5 more
core +1 more source
Sociodemographic and self-reported clinical history of study participants according to chikungunya virus (CHIKV) immune status during follow-up. [PDF]
, 2023 Sociodemographic and self-reported clinical history of study participants according to chikungunya virus (CHIKV) immune status during follow-up.
Jessica A. Plante (11649163) +18 more
core +1 more source
Journal of Infectious Diseases & Therapy, 2015 Background: The reemergence of Chikungunya virus (CHIKV) infection and the spread of the virus throughout the world call for a fast, reliable, and improved laboratory diagnostic procedures. The aim of this study was to determine if CHIKV genome is present in other body fluids besides plasma as a tool for developing non-invasive diagnostic method ...
Jones PH, Okeoma CM
openaire +1 more source
Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera
JCI Insight, 2022 Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus responsible for numerous outbreaks. Chikungunya can cause debilitating acute and chronic disease.
Pierre Roques +12 more
doaj +1 more source
Pathogenicity and virulence of chikungunya virus [PDF]
Chikungunya virus (CHIKV) is a mosquito-transmitted, RNA virus that causes an often-severe musculoskeletal illness characterized by fever, joint pain, and a range of debilitating symptoms.
Freppel, Wesley +3 more
core +1 more source
Development of Neutralization Assay Using an eGFP Chikungunya Virus
Viruses, 2016 Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and
Cheng-Lin Deng +11 more
doaj +1 more source
Chikungunya Immunopathology as It Presents in Different Organ Systems
Viruses, 2022 Chikungunya virus (CHIKV) is currently an urgent public health problem as high morbidity from the virus leaves populations with negative physical, social, and economic impacts.
Elizabeth M. Traverse +5 more
doaj +1 more source