Results 21 to 30 of about 12,242 (218)

Chikungunya as a cause of acute febrile illness in southern Sri Lanka. [PDF]

PLoS ONE, 2013
Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated febrile illness in unstudied rural and ...
Megan E Reller, Ufuoma Akoroda, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikaarachchi, John J Strouse, Robert Chua, Yan'an Hou, Angelia Chow, October M Sessions, Truls Østbye, Duane J Gubler, Christopher W Woods, Champica Bodinayake   +13 more
doaj   +1 more source

Genome-Wide Approaches to Unravel the Host Factors Involved in Chikungunya Virus Replication

Frontiers in Microbiology, 2022
Chikungunya virus (CHIKV), the causative agent of Chikungunya fever (CHIKVF) that is often characterized by fever, headache, rash, and arthralgia, is transmitted to humans by Aedes mosquito bites.
Atsushi Tanaka, Youichi Suzuki
doaj   +1 more source

Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate [PDF]

Vaccines, 2018
Our previous investigation of the nucleolar localisation sequence (NoLS) of chikungunya virus (CHIKV) capsid protein demonstrated the role of capsid in CHIKV virulence. Mutating the NoLS of capsid in CHIKV led to the development of a unique live-attenuated CHIKV vaccine candidate, termed CHIKV-NoLS.
Eranga Abeyratne, Joseph R. Freitas, Ali Zaid, Suresh Mahalingam, Adam Taylor   +4 more
openaire   +4 more sources

Computational analysis revealed miRNAs produced by Chikungunya virus target genes associated with antiviral immune responses and cell cycle regulation [PDF]

, 2021
Chikungunya virus (CHIKV) that causes chikungunya fever, is an alphavirus that belongs to the Togaviridae family containing a single-stranded RNA genome.
Khan, MAAK, Islam, MS
core   +1 more source

A Retrospective Seroprevalence Study of Dengue, Chikungunya and Co-Infection virus: a Hospital Based Study from Theni, Tamil Nadu [PDF]

, 2023
Viral-borne diseases have recently gained significant public health importance in the current world. The Viral Research and Diagnostic Laboratory (VRDL) located at Government Theni Medical College (GTMC), Theni, Tamil Nadu, conducts the diagnosis of ...
S.Krishnapriya, A. Dhanasezhiyan, S. Mathan Prasanth, R. Gopinath, G. Sucila Thangam   +4 more
core   +2 more sources

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.

PLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit, Jira Chansaenroj, Thanunrat Thongmee, Saovanee Benjamanukul, Nasamon Wanlapakorn, Chintana Chirathaworn, Yong Poovorawan   +6 more
doaj   +1 more source

Symptomatic Chikungunya Virus Infection and Pregnancy Outcomes: A Nested Case-Control Study in French Guiana

Viruses, 2022
During the Chikungunya epidemic in the Caribbean and Latin America, pregnant women were affected by the virus in French Guiana. The question of the impact of the virus on pregnancy was raised because of the lack of scientific consensus and published data
Célia Basurko, Najeh Hcini, Magalie Demar, Philippe Abboud, the CMFdeng study group, Mathieu Nacher, Gabriel Carles, Véronique Lambert, Séverine Matheus   +8 more
doaj   +1 more source

Chikungunya virus (CHIKV) inhibitors from natural sources: a medicinal chemistry perspective [PDF]

Journal of Natural Medicines, 2015
Abstract Chikungunya virus (CHIKV) is one of the re-emerging “neglected” tropical diseases whose recent outbreak affected not only Africa and South-East Asia but also several parts of America and Europe. To date, despite its serious nature, no antivirals or vaccines were developed in order to counter this resurgent infectious ...
Bhakat, Soumendranath, Soliman, Mahmoud E. S.   +1 more
openaire   +2 more sources

Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells [PDF]

, 2011
Background: Chikungunya virus (CHIKV) is a mosquito-borne, arthrogenic Alphavirus that causes large epidemics in Africa, South-East Asia and India. Recently, CHIKV has been transmitted to humans in Southern Europe by invading and now established Asian ...
Geertsema, C (Corinne), Corinne Geertsema, van Oers, MM, Paulina Andrade, Heldens, J.G.M., Geertsema, C., Vlak Just M, Pijlman Gorben P, Andrade, Paulina, Vlak, J.M. (Just), Vlak, J.M., Pijlman, G.P. (Gorben), Just M Vlak, Metz Stefan W, Goldbach, RW, Metz, S.W. (Stefan), Martina, B.E.E. (Byron), Geertsema Corinne, Metz, S.W.H., Stefan W Metz, Jacco G Heldens, Geertsema, C. (Corinne), Heldens Jacco G, Martina, Byron, Andrade, P. (Paulina), Metz, SW, Andrade Paulina, Heldens, J., Rob W Goldbach, Pijlman, G.P., Pijlman, GP, van Oers Monique M, Oers, M.M. (Monique) van, van Oers, M.M., Andrade, P, Goldbach, R.W., Gorben P Pijlman, Monique M van Oers, Vlak, JM, Goldbach Rob W, Heldens, JG, Byron E Martina, Martina, Byron E., Martina Byron E, Oers, M.M., van   +44 more
core   +1 more source

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source