Results 21 to 30 of about 1,052,896 (217)

Treatment of Chikungunya Virus (CHIKV) Using Targeted Immunotherapy

, 2022
Chikungunya virus (CHIKV) is the most common mosquito-borne Alphavirus infecting humans worldwide. Up to date, there are no antiviral treatments or vaccines approved to treat or prevent CHIKV for which treatments remain symptomatic based on clinical manifestations.
Fleury Augustin Nsole Biteghe, Chalomie Nyangone Ekome Toung, Jean De La Croix Ndong, Neelakshi Mungra, Tahir B. Dar, Arnaud John Kombe Kombe   +5 more
openaire   +2 more sources

Genome-Wide Approaches to Unravel the Host Factors Involved in Chikungunya Virus Replication

Frontiers in Microbiology, 2022
Chikungunya virus (CHIKV), the causative agent of Chikungunya fever (CHIKVF) that is often characterized by fever, headache, rash, and arthralgia, is transmitted to humans by Aedes mosquito bites.
Atsushi Tanaka, Youichi Suzuki
doaj   +1 more source

Chikungunya as a cause of acute febrile illness in southern Sri Lanka. [PDF]

PLoS ONE, 2013
Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated febrile illness in unstudied rural and ...
Megan E Reller, Ufuoma Akoroda, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikaarachchi, John J Strouse, Robert Chua, Yan'an Hou, Angelia Chow, October M Sessions, Truls Østbye, Duane J Gubler, Christopher W Woods, Champica Bodinayake   +13 more
doaj   +1 more source

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.

PLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit, Jira Chansaenroj, Thanunrat Thongmee, Saovanee Benjamanukul, Nasamon Wanlapakorn, Chintana Chirathaworn, Yong Poovorawan   +6 more
doaj   +1 more source

Symptomatic Chikungunya Virus Infection and Pregnancy Outcomes: A Nested Case-Control Study in French Guiana

Viruses, 2022
During the Chikungunya epidemic in the Caribbean and Latin America, pregnant women were affected by the virus in French Guiana. The question of the impact of the virus on pregnancy was raised because of the lack of scientific consensus and published data
Célia Basurko, Najeh Hcini, Magalie Demar, Philippe Abboud, the CMFdeng study group, Mathieu Nacher, Gabriel Carles, Véronique Lambert, Séverine Matheus   +8 more
doaj   +1 more source

Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate [PDF]

Vaccines, 2018
Our previous investigation of the nucleolar localisation sequence (NoLS) of chikungunya virus (CHIKV) capsid protein demonstrated the role of capsid in CHIKV virulence. Mutating the NoLS of capsid in CHIKV led to the development of a unique live-attenuated CHIKV vaccine candidate, termed CHIKV-NoLS.
Eranga Abeyratne, Joseph R. Freitas, Ali Zaid, Suresh Mahalingam, Adam Taylor   +4 more
openaire   +4 more sources

Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells [PDF]

, 2011
Background: Chikungunya virus (CHIKV) is a mosquito-borne, arthrogenic Alphavirus that causes large epidemics in Africa, South-East Asia and India. Recently, CHIKV has been transmitted to humans in Southern Europe by invading and now established Asian ...
Geertsema, C (Corinne), Corinne Geertsema, van Oers, MM, Paulina Andrade, Heldens, J.G.M., Geertsema, C., Vlak Just M, Pijlman Gorben P, Andrade, Paulina, Vlak, J.M. (Just), Vlak, J.M., Pijlman, G.P. (Gorben), Just M Vlak, Metz Stefan W, Goldbach, RW, Metz, S.W. (Stefan), Martina, B.E.E. (Byron), Geertsema Corinne, Metz, S.W.H., Stefan W Metz, Jacco G Heldens, Geertsema, C. (Corinne), Heldens Jacco G, Martina, Byron, Andrade, P. (Paulina), Metz, SW, Andrade Paulina, Heldens, J., Rob W Goldbach, Pijlman, G.P., Pijlman, GP, van Oers Monique M, Oers, M.M. (Monique) van, van Oers, M.M., Andrade, P, Goldbach, R.W., Gorben P Pijlman, Monique M van Oers, Vlak, JM, Goldbach Rob W, Heldens, JG, Byron E Martina, Martina, Byron E., Martina Byron E, Oers, M.M., van   +44 more
core   +2 more sources

Challenges in Surveillance for Chikungunya Virus (CHIKV) Infection

Online Journal of Public Health Informatics, 2015
We describe challenges and lessons learned using biosurveillance methods for identifying Chikungunya (CHIKV) infections. Surveillance was performed using VA ESSENCE, electronic laboratory data and facility reports. As of Aug. 14, 2014, 21 confirmed/probable cases were identified at 10 hospitals.
Lucero-Obusan, Cynthia A., Schirmer, Patricia, Oda, Gina, Holodniy, Mark   +3 more
openaire   +2 more sources

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source

Persistent Cervical Infection with the Chikungunya Virus [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Chikungunya virus (CHIKV) induces an acute infection known as chikungunya fever; however, the persistence of CHIKV infections has been reported. This report investigated the persistence of CHIKV over six months in the cervix of two infected women.
José Eduardo Pérez-Pérez, Oscar Guzmán-Martínez, Jesús Miguel Torres-Flores, Clara Luz Sampieri, Julio Isael Pérez-Carreón, Nayali López-Balderas, Miguel Ángel Barragán, Guillermo Mendoza-Cervantes, Fabio García-García, Alma Campos, David Sánchez-Marín, Hilda Montero   +11 more
doaj   +1 more source