Results 21 to 30 of about 15,637 (220)
Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.
PLoS ONE, 2021 Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit +6 more
doaj +1 more source
Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate [PDF]
Vaccines, 2018 Our previous investigation of the nucleolar localisation sequence (NoLS) of chikungunya virus (CHIKV) capsid protein demonstrated the role of capsid in CHIKV virulence. Mutating the NoLS of capsid in CHIKV led to the development of a unique live-attenuated CHIKV vaccine candidate, termed CHIKV-NoLS.
Eranga Abeyratne +4 more
openaire +4 more sources
Persistent Cervical Infection with the Chikungunya Virus [PDF]
Revista da Sociedade Brasileira de Medicina TropicalChikungunya virus (CHIKV) induces an acute infection known as chikungunya fever; however, the persistence of CHIKV infections has been reported. This report investigated the persistence of CHIKV over six months in the cervix of two infected women.
José Eduardo Pérez-Pérez +11 more
doaj +1 more source
Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]
, 2019 The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D. +25 more
core +2 more sources
Challenges in Surveillance for Chikungunya Virus (CHIKV) Infection
Online Journal of Public Health Informatics, 2015 We describe challenges and lessons learned using biosurveillance methods for identifying Chikungunya (CHIKV) infections. Surveillance was performed using VA ESSENCE, electronic laboratory data and facility reports. As of Aug. 14, 2014, 21 confirmed/probable cases were identified at 10 hospitals.
Lucero-Obusan, Cynthia A. +3 more
openaire +2 more sources
Low chikungunya virus seroprevalence two years after emergence in Fiji
International Journal of Infectious Diseases, 2020 Objectives: In Fiji, autochthonous chikungunya virus (CHIKV) infection was first detected in March 2015. In a previous serosurvey conducted during October–November 2015, we reported a prevalence of anti-CHIKV IgG antibodies of 0.9%. In the present study,
Maite Aubry +12 more
doaj +1 more source
Viruses, 2022 During the Chikungunya epidemic in the Caribbean and Latin America, pregnant women were affected by the virus in French Guiana. The question of the impact of the virus on pregnancy was raised because of the lack of scientific consensus and published data
Célia Basurko +8 more
doaj +1 more source
Recent Progress in Vaccine Development Against Chikungunya Virus
Frontiers in Microbiology, 2019 Chikungunya fever (CHIKF) is an acute infectious disease that is mediated by the mosquito-transmitted chikungunya virus (CHIKV). People infected with CHIKV may experience high fever, severe joint pain, skin rash, and headache.
Shan Gao +3 more
doaj +1 more source
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]
, 2016 Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano +16 more
core +5 more sources
PLoS ONE, 2020 The first autochthonous case of chikungunya virus (CHIKV) infection in Brazil was in September 2014 in the State of Amapá, and from there it rapidly spread across the country.
Joelma D Monteiro +16 more
doaj +1 more source