Results 11 to 20 of about 1,377,517 (218)

Cellular Attachment and Entry Factors for Chikungunya Virus

Viruses, 2019
Chikungunya virus (CHIKV) is clinically the most relevant member of the Alphavirus genus. Like alphaviruses in general, CHIKV has the capacity to infect a large variety of cells, tissues, and species.
Barbara S. Schnierle
doaj   +2 more sources

Development of Neutralization Assay Using an eGFP Chikungunya Virus

Viruses, 2016
Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and
Cheng-Lin Deng, Si-Qing Liu, Dong-Gen Zhou, Lin-Lin Xu, Xiao-Dan Li, Pan-Tao Zhang, Peng-Hui Li, Han-Qing Ye, Hong-Ping Wei, Zhi-Ming Yuan, Cheng-Feng Qin, Bo Zhang   +11 more
doaj   +2 more sources

Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus [PDF]

Viruses, 2019
Chikungunya virus (CHIKV) has caused extensive outbreaks in several countries within the Americas, Asia, Oceanic/Pacific Islands, and Europe. In humans, CHIKV infections cause a debilitating disease with acute febrile illness and long-term polyarthralgia.
César López-Camacho, Young Chan Kim, Joshua Blight, Marcos Lazaro Moreli, Eduardo Montoya-Diaz, Juha T Huiskonen, Beate Mareike Kümmerer, Arturo Reyes-Sandoval   +7 more
doaj   +2 more sources

Chikungunya infection and horner syndrome

IDCases, 2018
We describe an infant with Chikungunya virus (CHIKV) infection who developed Horner syndrome. The infant had diagnostic confirmation of CHIKV infection by IgM-ELISA positive in serum and cerebrospinal fluid, and clinical signs of Horner syndrome ...
Lucas Victor Alves, Filipe Marinho Pinheiro da Câmara, Mayara Batista Granha, Alfredo Meneses Neto, Bezerra Alves, JG   +4 more
doaj   +2 more sources

Chikungunya Virus in US Travelers Returning from India, 2006

Emerging Infectious Diseases, 2007
Chikungunya virus (CHIKV), a mosquitoborne alphavirus; is endemic in Africa and Asia. In 2005–2006, CHIKV epidemics were reported in islands in the Indian Ocean and in southern India.
Robert S. Lanciotti, Olga L. Kosoy, Janeen J. Laven, Amanda J. Panella, Jason O. Velez, Amy J. Lambert, Grant L. Campbell   +6 more
doaj   +2 more sources

A single-dose chimeric Newcastle disease virus (NDV)/chikungunya virus (CHIKV) is an effective CHIKV vaccine candidate. [PDF]

J Virol
ABSTRACT With the broad spread of the chikungunya virus (CHIKV), there is an increasing demand for more effective and protective vaccines. In this study, we first developed a Newcastle disease virus (NDV) vector vaccine candidate expressing the complete envelope (E3–E1) protein of CHIKV.
Zhang Q-Y, Zhang Y, Zhang Z-R, Li Y, Yan Q, Zhang Y-N, Zhang B.   +6 more
europepmc   +4 more sources

Ion-Channel-Targeting Drugs for Chikungunya Virus

Molecules
Alphaviruses are transmitted by Aedes mosquitoes and cause large-scale epidemics worldwide. Chikungunya virus (CHIKV) infection can cause febrile seizures known as chikungunya fever (CHIKF), which ultimately leads to severe joint pain and myalgia.
Hiya Lahiri, Kingshuk Basu, Isaiah T. Arkin   +2 more
doaj   +2 more sources

Genomic surveillance of the Chikungunya Virus (CHIKV) in Northeast Brazil after the first outbreak in 2014. [PDF]

Rev Soc Bras Med Trop, 2020
We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak.Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018.Of ...
Rodrigues AM, Souza RRM, Fonseca LMDS, Rolo CA, Carvalho RH, Sardi SI, Campos GS.   +6 more
europepmc   +6 more sources

Chikungunya virus (CHIKV) seroprevalence in the South Pacific populations of the Cook Islands and Vanuatu with associated environmental and social factors. [PDF]

PLoS Negl Trop Dis, 2022
Background Arthropod-borne diseases pose a significant and increasing risk to global health. Given its rapid dissemination, causing large-scale outbreaks with severe human infections and economic loss, the Chikungunya virus (CHIKV) is one of the most important arboviruses worldwide. Despite its significance, the
Saretzki CEB, Dobler G, Iro E, May Y, Tou D, Lockington E, Ala M, Heussen N, Phiri BSJ, Küpper T.   +9 more
europepmc   +5 more sources

Recent advances in antiviral drugs for Chikungunya virus (CHIKV): Targets, mechanisms, and development strategies. [PDF]

Acta Pharm Sin B
Chikungunya virus (CHIKV), an alphavirus transmitted by Aedes mosquitoes, has frequently caused outbreaks in tropical and subtropical regions worldwide, posing a significant public health threat. CHIKV infection leads to chikungunya fever, characterized by fever, rash, and persistent joint pain, with approximately 30%-40% of patients developing chronic
Jiang X, Zhao Y, Lu H, Li K, Gao H.
europepmc   +3 more sources