Results 61 to 70 of about 1,981,808 (273)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

Clinical characteristics of febrile patients with acute dengue vs. other acute febrile illness, Nicaragua.

open access: yes, 2016
Clinical characteristics of febrile patients with acute dengue vs. other acute febrile illness, Nicaragua.
Megan E. Reller (491579)   +8 more
core   +1 more source

Persistence of anti-leptospiral IgM, IgG and agglutinating antibodies in patients presenting with acute febrile illness in Barbados 1979-1989. [PDF]

open access: yes, 2001
The persistence of anti-leptospiral IgM and IgG antibodies and agglutinating antibodies was studied in serologically confirmed cases of severe leptospirosis during the acute illness and over periods of several years after recovery.
Wheeler, JG   +3 more
core   +1 more source

Demographic characteristics of enrolled acute febrile illness (AFI) patients in Bangladesh, May 2019-March 2020.

open access: yes, 2022
Demographic characteristics of enrolled acute febrile illness (AFI) patients in Bangladesh, May 2019-March 2020.
Fahmida Chowdhury (2635042)   +21 more
core   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

Rickettsia conorii infection with fatal complication

open access: yesAutopsy and Case Reports, 2022
Rickettsial diseases (RD) are a group of endotheliotropic infectious diseases caused by different species of genera Rickettsia. RD are not an uncommon disease and may be misdiagnosed during the evaluation of acute febrile illness due to a lack of ...
Sanjoli Chugh   +5 more
doaj  

Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in resource-limited settings: an expert consensus [PDF]

open access: yes, 2016
Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.
Zorzet, A.   +105 more
core   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

open access: yesAdvanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu   +12 more
wiley   +1 more source

Incidence of acute undifferentiated febrile illnesses in an urban slum of Delhi: A longitudinal cohort study

open access: yesClinical Epidemiology and Global Health
Objective: Acute undifferentiated febrile illness (AUFI) is a neglected topic in health care. It has considerable morbidity and mortality worldwide. Slum dwellers are at high risk due to poor living conditions.
Debadatta Nayak   +5 more
doaj   +1 more source

A case series of scrub meningoencephalitis from a tertiary care center in North India

open access: yesAnnals of Indian Academy of Neurology, 2023
Scrub typhus infection is reemerging leading cause of acute febrile illnesses in post-rainy or monsoon season in Southeast Asia. It is caused by Orientia tsutsugamushi and spread by the bite of chiggers, larval forms of trombiculid mites.
Vikas Suri   +6 more
doaj   +1 more source

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