Results 71 to 80 of about 1,512,505 (195)

Pyruvate Kinase M2 Upregulation Is Associated With Guillain–Barré Syndrome Risk and Immune Dysregulation: Insights From Mendelian Randomization and the Experimental Autoimmune Neuritis Model

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Objective This study aimed to investigate the potential involvement of pyruvate kinase M2 (PKM2) in the pathogenesis of Guillain–Barré syndrome (GBS). Methods Mendelian randomization (MR) analysis was used to evaluate the causal association between PKM2 expression and GBS susceptibility, with mediation analysis performed to explore immune cell‐
Shuping Liu, Huiying Lu, Yuge Kang, Zheman Xiao, Qian Min, Yi Dong   +5 more
wiley   +1 more source

Voice and Speech in Atypical Parkinsonian Disorders

Movement Disorders Clinical Practice, Volume 13, Issue 8, Page 1848-1860, August 2026.
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel, Farwa Ali, Michiko Bruno, Heather Davis Cuevas, Rohit Dhall, Kylie Dunne‐Platero, Lawrence I. Golbe, Ihtsham Haq, Nicole Herndon, Lawrence S. Honig, Kyurim Kang, Sarah Kremen, Guillaume Lamotte, Nikolaus R. McFarland, Michela Mir, Leila Montaser‐Kouhsari, Alexander Pantelyat, Joel Page, Hylan Pickett, Laura Purcell Verdun, Kelly Richardson, Jessica Shurer, Michelle Troche, Rene L. Utianski, Katya Villarreal‐Cavazos, Tuhin Virmani, Anne‐Marie Wills, as the Diagnosis and Treatment Working Group, CurePSP Center of Care (CoC) Network, Farwa Ali, Michiko Bruno, Timothy Chang, Rohit Dhall, Kimiko Domoto‐Reilly, Lawrence I. Golbe, Ihtsham Haq, Lawrence S. Honig, Sarah Kremen, Guillaume Lamotte, Zoltan Mari, Nikolaus R. McFarland, Leila Montaser‐Kouhsari, Alexander Pantelyat, Federico Rodriguez‐Porcel, Junaid Siddiqui, Jessica Shurer, Christopher Spears, Tuhin Virmani, Anne‐Marie Wills   +48 more
wiley   +1 more source

Efficient Assembly of Coxsackievirus A16 Virus‐Like Particles in Insect Cells via VP4‐Deficient P1 Expression

Entomological Research, Volume 56, Issue 8, August 2026.
ABSTRACT Coxsackievirus A16 (CVA16) is a major causative agent of hand, foot, and mouth disease (HFMD), yet efficient virus‐like particle (VLP)–based vaccine development remains challenging due to enteroviral structural complexity and the cytotoxicity of the 3CD protease required for polyprotein processing.
Hyun‐Soo Kim, Hyuk‐Jin Moon, Ra‐Mi Woo, Jae‐Bang Choi, Beom‐Ku Han, Soo Dong Woo   +5 more
wiley   +1 more source

Acute flaccid paralysis: An approach to diagnosis

, 2017
Acute flaccid paralysis (AFP) is a common presentation to the emergency department and can present with paralysis of single to several limbs. Here is a case with AFP presented to highlight the approach to diagnosis.
A Yadav, S Chaudhari, PP Gupta, P Bhattarai, B Aryal, Ashok Kumar Yadav   +5 more
core   +1 more source

Novel recombinant human adenoviruses: A call for enhanced molecular surveillance, diagnosis, and management in pediatric acute respiratory infections

Pediatric Investigation, EarlyView.
Zhen Zhu, Naiying Mao
wiley   +1 more source

Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)

Australian Veterinary Journal, Volume 104, Issue 8, Page 497-508, August 2026.
Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
wiley   +1 more source

Surveillance of acute flaccid paralysis in Hong Kong: 1997 to 2002 [PDF]

, 2005
Objectives. To describe the characteristics of patients reported with acute flaccid paralysis between 1997 and 2002, and to evaluate the performance of the acute flaccid paralysis surveillance system using indicators recommended by the World Health ...
Lau, YL, Lim, WL, Leung, NK, Lam, TH, Lam, RMK, Tsang, THF, Chan, KY   +6 more
core  

Enterovirus 74 infection in children. [PDF]

PLoS ONE, 2013
Enterovirus 74 (EV74) is a rarely detected viral infection of children. In 2010, EV74 was identified in New Zealand in a 2 year old child with acute flaccid paralysis (AFP) through routine polio AFP surveillance.
Matthew Peacey, Richard J Hall, Jing Wang, Angela K Todd, Seiha Yen, Jasmine Chan-Hyams, Christy J Rand, Jo-Ann Stanton, Q Sue Huang   +8 more
doaj   +1 more source

Enterovirus D68 Detected in Hospitalized Children With Severe Acute Respiratory Infections in Zambia

Influenza and Other Respiratory Viruses, Volume 20, Issue 8, August 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a cause of severe acute respiratory infections (SARI) and is associated with acute flaccid paralysis. However, data on EV‐D68 in Africa, where SARI remains a leading cause of morbidity and mortality among children, remain limited.
Idah Mweene Ndumba, Michiko Okamoto, Paul Simusika, Takeaki Imamura, Mwaka Monze, Mayuko Saito, Hitoshi Oshitani   +6 more
wiley   +1 more source

Evaluation of the Surveillance System for Acute Flaccid Paralysis (AFP) in Iran during the Years 2003-2007 and Its Comparison with Worldwide Standards

مجله دانشکده پزشکی اصفهان, 2014
Background: This study aimed to evaluate the surveillance system for acute flaccid paralysis (AFP) in Iran during the years 2003-2007 and compare it with worldwide standards. Methods: In this cross-sectional study, we analyzed all cases of acute flaccid
Esmaeil Akhtar, Reza Fadaei-Nobari
doaj