Results 111 to 120 of about 61,141 (261)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Volume 78, Issue 6, Page 749-760, June 2026.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1192-1203, June 2026.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Zinc Deficiency in Acute Gastroenteritis and Upper Respiratory Tract Infections

, 2011
Aim. The objective was to study zinc deficiency in acute gastroenteritis and upper respiratory tract infections. Methods. A total of 203 children were enrolled in this case— control study.
Abdulkadir Bozaykut, Duygu Somen Bayoglu, Rabia Gonul Sezer, Ilke Ozahi Ipek   +3 more
core   +1 more source

Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Phytochemistry and bioactivity of thymol chemotype Thymus vulgaris L. hydrolate. ABSTRACT The increasing prevalence of antimicrobial resistance necessitates the development of alternative antimicrobial agents derived from natural sources. This study evaluated the volatile chemical profile and antimicrobial activity of a thymol‐containing hydrolate ...
Stefania Garzoli, Joel Horacio Elizondo‐Luevano, Anis Ben Hsouna, Rania Ben Saad, Miroslava Kačániová   +4 more
wiley   +1 more source

ACUTE GASTROENTERITIS ASSOCIATED WITH NOROVIRUS GII.4 VARIANTS

Arquivos de Gastroenterologia
BACKGROUND: Norovirus (NoV) is an important etiologic agent of acute gastroenteritis and infects individuals of all ages, especially children in Brazil and worldwide.
Fabiana Lopes de PAULA, Silvia Inês SARDI, Dellane Martins TIGRE, Flora Maria de Campos FERNANDES, Gúbio Soares CAMPOS   +4 more
doaj   +1 more source

Acute Disseminated Encephalomyelitis Presenting as Fever of Unknown Origin in a 4‐Year‐Old Boy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A 4‐year‐old boy presented with prolonged fever of unknown origin and systemic inflammation without early neurological signs. MRI revealed multifocal demyelination, and MOG antibodies were positive. He was diagnosed with ADEM and treated with steroids and IVIg, but relapsed twice, consistent with multiphasic disseminated encephalomyelitis ...
Pedro Pau
wiley   +1 more source

EPIDEMIC INVESTIGATION OF AN ACUTE GASTROENTERITIS OUTBREAK IN DASLANA VILLAGE OF AHMEDABAD, GUJARAT

National Journal of Medical Research, 2013
Background: Diarrhoeal diseases affect millions of people around the world and have greatest impact on children, especially those in developing countries. Diarrhoeal disease outbreaks are cause of major public health emergencies in India.
Atul V Trivedi, Rohit V Ram, Keyur B Patel   +2 more
doaj  

Managing Acute Gastroenteritis Among Children; Oral Rehydration, Maintenance, and Nutritional Therapy [PDF]

Acute gastroenteritis remains a common illness among infants and children throughout the world. Among children in the United States, acute diarrhea accounts for >1.5 million outpatient visits, 200,000 hospitalizations, and approximately 300 deaths/year ...

core  

Strawberry Tongue due to Streptococcal Toxic Shock Syndrome

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Strawberry tongue is associated with streptococcal toxic shock syndrome (TSS). Streptococcal TSS should be considered as one of the differential diagnoses for patients with shock and strawberry tongue. Our case is the first to report desquamation of strawberry tongue in patients with TSS.
Hiro Takefuji, Junpei Komagamine, Kei Ota   +2 more
wiley   +1 more source