Results 131 to 140 of about 61,141 (261)
Therapy of acute gastroenteritis: role of antibiotics
Acute infectious diarrhoea remains a very common health problem, even in the industrialized world. One of the dilemmas in assessing patients with acute diarrhoea is deciding when to test for aetiological agents and when to initiate antimicrobial therapy.
Zollner-Schwetz, I., Krause, R.
core +1 more source
ABSTRACT Background and Aims Rotavirus is a leading cause of severe diarrhoeal disease in young children worldwide. In 2024, Iran introduced the pentavalent oral vaccine Rotasiil® into its national immunization program. This study aimed to estimate its potential epidemiological impact using an agent‐based modeling (ABM) approach.
Amirhesam Moosazadeh +2 more
wiley +1 more source
Background: Acute gastroenteritis in pediatric patients entails high rates of morbidity and mortality. One of its complications is dehydration, which should be managed carefully.
Parsa Yousefi +2 more
doaj
Development of a Clinical Severity Score for Indian Sickle Cell Anaemia Patients
ABSTRACT Background Sickle cell anaemia (SCA) is a monogenic disorder but shows variable disease severity. We evaluated the utility of paediatric severity scores (PSS) in Indian patients and developed two modified scores: Indian Severity Score 1 (ISS1) by adding four clinical parameters to PSS, and ISS2 by excluding four biochemical measures from ISS1.
Suraj S. Nongmaithem +6 more
wiley +1 more source
Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede +14 more
wiley +1 more source
Dehydration in acute gastroenteritis [PDF]
openaire +2 more sources
Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano +22 more
wiley +1 more source
Pathogenic Mechanisms of V. vulnificus and Its Role in the Development of Sepsis
Sorafenib attenuates urethral scar formation by inhibiting β‐catenin signaling in fibroblasts, which downregulates the SLC7A11/GPX4 antioxidant axis and triggers ferroptosis. This β‐catenin–ferroptosis coupling effectively suppresses fibrogenesis, highlighting sorafenib as a promising drug‐repurposing candidate for urethral stricture.
Zhongying Yu +7 more
wiley +1 more source
The Piglet As A Model Of Norwalk Gastroenteritis
Norwalk-like viruses (NLV) are the most important cause of acute gastroenteritis in humans. However, little is known about their pathogenesis since no cell culture or animal model is available yet.
McPhatter, Lisa Anastasia
core
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source

