Results 1 to 10 of about 3,497,436 (306)

Genetic polymorphism of the Dab2 gene and its association with Type 2 Diabetes Mellitus in the Chinese Uyghur population [PDF]

PeerJ, 2023
Objective The human Disabled-2 (Dab2) protein is an endocytic adaptor protein, which plays an essential role in endocytosis of transmembrane cargo, including low-density lipoprotein cholesterol (LDL-C).
Yan-Peng Li, Dilare Adi, Ying-Hong Wang, Yong-Tao Wang, Xiao-Lei Li, Zhen-Yan Fu, Fen Liu, Aibibanmu Aizezi, Jialin Abuzhalihan, Mintao Gai, Xiang Ma, Xiao-mei Li, Xiang Xie, YiTong Ma   +13 more
doaj   +2 more sources

piR-1919609 Is an Ideal Potential Target for Reversing Platinum Resistance in Ovarian Cancer

Technology in Cancer Research & Treatment
Purpose PIWI-interacting RNAs (piRNAs) are a type of noncoding small RNA that can interact with PIWI-like RNA-mediated gene silencing (PIWIL) proteins to affect biological processes such as transposon silencing through epigenetic effects.
Ying Yan MD, Dan Tian MD, Bingbing Zhao PhD, Zhuang Li PhD, Zhijiong Huang PhD, Kuina Li MD, Xiaoqi Chen MD, Lu Zhou MD, Yanying Feng MD, Zhijun Yang PhD   +9 more
doaj   +1 more source

Epigenetically associated IGF2BP3 upregulation promotes cell proliferation by regulating E2F1 expression in hepatocellular carcinoma

Scientific Reports
RNA-binding proteins (RBPs) are a class of proteins that primarily function by interacting with different types of RNAs and play a critical role in regulating the transcription and translation of cancer-related genes.
Chenghao Liu, Yicheng Zhuo, Xiaofeng Yang, Chen Yang, Min Shu, Bowen Hou, Jun Hou, Xueling Chen, Lianghai Wang, Xiangwei Wu   +9 more
doaj   +1 more source

Massive sympathetic nerve infiltration in advanced hepatic alveolar echinococcosis: a case report and review of the literature

BMC Infectious Diseases, 2022
Background Alveolar echinococcosis is a zoonotic disease that mostly affects the liver, with vascular invasion and a protean clinical symptom. However, no reports of sympathetic nerve infiltration in hepatic alveolar echinococcosis have been reported ...
Zongding Wang, Tiemin Jiang, Tuerganaili Aji, Hao Wen   +3 more
doaj   +1 more source

Comparative effectiveness of monotherapy vs. combination therapy for postoperative central nervous system infections in neurosurgical patients: a retrospective cohort study

BMC Infectious Diseases
Background Although clinical guidelines recommend vancomycin-based combination therapy for patients with postoperative intracranial infections in neurosurgery, the trend of global bacterial resistance and the management of antimicrobial agents have made ...
Muyun Li, Wei Meng, Linna An, Xiaoqi Lin, Shangjie Yang, Qiang Fu, Qiuxia Shi, Dongfeng Li, Jie Wang, Jianhua Wang, Yubo Wang   +10 more
doaj   +1 more source

Aberrant activation of CYR61 enhancers in colorectal cancer development

Journal of Experimental & Clinical Cancer Research, 2019
Background High expression of secreted matricellular protein cysteine-rich 61 (CYR61) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation has been shown to correlate with expression of key genes involved in cancer ...
Lingzhu Xie, Xuhong Song, Hao Lin, Zikai Chen, Qidong Li, Tangfei Guo, Tian Xu, Ting Su, Man Xu, Xiaolan Chang, Long-Kun Wang, Bin Liang, Dongyang Huang   +12 more
doaj   +1 more source

Defective expression of C20orf54 in esophageal dysplasia: a possible biomarker of esophageal carcinoma for early detection

World Journal of Surgical Oncology, 2022
Background C20orf54 has been identified as an esophageal squamous cell carcinoma (ESCC) susceptibility gene in previous genome-wide association studies.
Man Li, Jing Kong, Lianghai Wang, Hongjuan Yan, Weihua Liang, Ning Wang, Jin Zhao   +6 more
doaj   +1 more source

INCIDENCE OF TRAVELERS’ DIARRHEA AMONG JAPANESE VISITING THAILAND [PDF]

, 2004
A cross-sectional survey of 327 Japanese short-term travelers (≤3 weeks) arriving in Bangkok, Thailand was conducted to assess the incidence of travelers’ diarrhea (TD) as well as their symptoms and treatment-seeking behaviors. The incidence of the first
Mitsui, Yoshinori, Boonshuyar, Chaweewon, Chanyasanha, Charnchudhi, Shimada, Masaaki, Moji, Kazuhiko   +4 more
core   +1 more source

On the development and practice of translational medicine

生物医学转化, 2021
Translational medicine is an innovative research model that connects basic research and clinicalapplication. The development of translational medicine and the promotion of the transformation of results can provide advanced concepts and methods for the ...
Ayixiemuguli·Alimas, Wen Hao
doaj   +1 more source

Experimental study on the optimization of ANM33 release in foam cells

Open Life Sciences, 2023
Given the miR-33’s mechanistic relationships with multiple etiological factors in the pathogenesis of atherosclerosis (AS), we investigated the therapeutic potentials of dual-targeted microbubbles (HA-PANBs) in foam cell-specific release of anti-miR-33 ...
Yuan Chen, Liu Liyun, Tayier Baihetiya, Ma Ting, Guan Lina, Mu Yuming, Li Yanhong   +6 more
doaj   +1 more source