Results 31 to 40 of about 3,969,633 (257)

piR-1919609 Is an Ideal Potential Target for Reversing Platinum Resistance in Ovarian Cancer

Technology in Cancer Research & Treatment
Purpose PIWI-interacting RNAs (piRNAs) are a type of noncoding small RNA that can interact with PIWI-like RNA-mediated gene silencing (PIWIL) proteins to affect biological processes such as transposon silencing through epigenetic effects.
Ying Yan MD, Dan Tian MD, Bingbing Zhao PhD, Zhuang Li PhD, Zhijiong Huang PhD, Kuina Li MD, Xiaoqi Chen MD, Lu Zhou MD, Yanying Feng MD, Zhijun Yang PhD   +9 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Epigenetically associated IGF2BP3 upregulation promotes cell proliferation by regulating E2F1 expression in hepatocellular carcinoma

Scientific Reports
RNA-binding proteins (RBPs) are a class of proteins that primarily function by interacting with different types of RNAs and play a critical role in regulating the transcription and translation of cancer-related genes.
Chenghao Liu, Yicheng Zhuo, Xiaofeng Yang, Chen Yang, Min Shu, Bowen Hou, Jun Hou, Xueling Chen, Lianghai Wang, Xiangwei Wu   +9 more
doaj   +1 more source

Massive sympathetic nerve infiltration in advanced hepatic alveolar echinococcosis: a case report and review of the literature

BMC Infectious Diseases, 2022
Background Alveolar echinococcosis is a zoonotic disease that mostly affects the liver, with vascular invasion and a protean clinical symptom. However, no reports of sympathetic nerve infiltration in hepatic alveolar echinococcosis have been reported ...
Zongding Wang, Tiemin Jiang, Tuerganaili Aji, Hao Wen   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Incidence-prevalence ratio and incidence-mortality ratio (with uncertainty bounds) by States/UTs in India, 2019.

, 2022
Incidence-prevalence ratio and incidence-mortality ratio (with uncertainty bounds) by States/UTs in India, 2019.
Damodar Sahu (3203208), Shashi Kant (3721432), Lakshmi P. V. M. (13113394), Chinmoyee Das (13113385), Vishnu Vardhana Rao Mendu (12667208), Elangovan Arumugam (13113391), Arvind Pandey (434795), Sanjay Mehendale (281610), Shobini Rajan (12360177), Pradeep Kumar (310858), Sanjay K. Rai (13113388), Shanta Dutta (185742), Dandu Chandra Sekhar Reddy (13113400), Arvind Kumar (227201), H. Sanayaima Devi (13113397), Sheela Godbole (628538)   +15 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Comparative effectiveness of monotherapy vs. combination therapy for postoperative central nervous system infections in neurosurgical patients: a retrospective cohort study

BMC Infectious Diseases
Background Although clinical guidelines recommend vancomycin-based combination therapy for patients with postoperative intracranial infections in neurosurgery, the trend of global bacterial resistance and the management of antimicrobial agents have made ...
Muyun Li, Wei Meng, Linna An, Xiaoqi Lin, Shangjie Yang, Qiang Fu, Qiuxia Shi, Dongfeng Li, Jie Wang, Jianhua Wang, Yubo Wang   +10 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source