Results 131 to 140 of about 8,879,078 (347)

Lymph Node Status in Colorectal Cancer; Is There a Case for Auditing the Pathologist and the Surgeon? [PDF]

Iranian Journal of Colorectal Research, 2019
The significance of nodal metastasis as a prognostic factor in colorectal cancer is universally recognised and accepted. This articlediscusses the various factors that govern lymph node harvest and how to improve that.
Emil Salmo, Najib Haboubi
doaj  

Strategies to Prevent Surgical Site Infections in Acute Care Hospitals: 2014 Update

Infection Control & Hospital Epidemiology, 2014
Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections (HAIs).
D. Anderson, Kelly L. Podgorny, Sandra I. Berríos-Torres, Dale W. Bratzler, E. Dellinger, L. Greene, A. Nyquist, Lisa Saiman, D. Yokoe, Lisa L. Maragakis, Keith S. Kaye   +10 more
semanticscholar   +1 more source

Irish hospitals 1956-1971 [PDF]

, 1971
This book details the Irish hospital activities funded by the Hospitals Trust Ltd (the Irish Hospital Sweepstakes) between 1956 and 1971, along with photographs of the hospitals ...
Hospitals' Trust (1940) Ltd
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The challenges in monitoring and preventing patient safety incidents for people with intellectual disabilities in NHS acute hospitals: evidence from a mixed-methods study

BMC Health Services Research, 2014
BackgroundThere has been evidence in recent years that people with intellectual disabilities in acute hospitals are at risk of preventable deterioration due to failures of the healthcare services to implement the reasonable adjustments they need. The aim
I. Tuffrey-Wijne, L. Goulding, V. Gordon, E. Abraham, N. Giatras, C. Edwards, S. Gillard, S. Hollins   +7 more
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Strategies to identify medical patients suitable for management through same-day emergency care services: A systematic review

Clinical Medicine
Same-day emergency care (SDEC) in unplanned and emergency care is an NHS England (NHSE) priority. Optimal use of these services requires rapid identification of suitable patients. NHSE suggests the use of one tool for this purpose. This systematic review
Catherine Atkin, Rhea Khosla, John Belsham, Hannah Hegarty, Cait Hennessy, Elizabeth Sapey   +5 more
doaj   +1 more source

A retrospective analysis of outcomes in low- and intermediate–high-risk pulmonary embolism patients managed on an ambulatory medical unit in the UK

ERJ Open Research, 2019
Pulmonary embolism (PE) is common and guidelines recommend outpatient care only for PE patients with low predicted mortality. Outcomes for patients with intermediate-to-high predicted mortality managed as outpatients are unknown.
Michael E. Reschen, Jonathan Raby, Jordan Bowen, Sudhir Singh, Daniel Lasserson, Christopher A. O'Callaghan   +5 more
doaj   +1 more source

Dementia care in the acute hospital setting: issues and strategies [PDF]

, 2014
This report identifies a range of strategies to improve the outcomes for people with dementia. Executive summary: Australia is facing a huge healthcare challenge with an ever increasing demand for appropriate acute care services for people with dementia.

core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source