Results 31 to 40 of about 8,444 (132)

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Role of “Sural Sparing” Pattern (Absent/Abnormal Median and Ulnar with Present Sural SNAP) Compared to Absent/Abnormal Median or Ulnar with Normal Sural SNAP in Acute Inflammatory Demyelinating Polyneuropathy

Frontiers in Neurology, 2017
BackgroundSural sparing defined as absent/abnormal median sensory nerve action potential (SNAP) amplitude or absent/abnormal ulnar SNAP amplitude with a normal sural SNAP amplitude is thought to be a marker for inflammatory demyelinating polyneuropathies.
Spurthi Sunil Surpur, Raghav Govindarajan   +1 more
doaj   +1 more source

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Differentiating demyelinating from axonal polyneuropathies helps for accurate diagnosis and treatment. However, the current clinical tools lack sensitivity to confirm demyelination in peripheral nerves, particularly for proximal nerves.
Jesus E. Fajardo, Vivian B. Truong, Yang Xuan, Sara E. Benitez, Mary L. Vo, Bo Hu, Richard D. Dortch, Jun Li, Yongsheng Chen   +8 more
wiley   +1 more source

Childhood Vasculitis Syndrome Mimicking Guillain Barre Syndrome

Indian Pediatrics Case Reports, 2022
Background: Childhood vasculitis is a heterogeneous disorder, characterized by inflammation of the blood vessel walls. Multiple organs and/or tissues are affected, either simultaneously or successively.
Pradeep Kumar Jena, Swasthi Kabi Satpathy, Sarthak Naik, Alok Satyaprakash Nayak   +3 more
doaj   +1 more source

Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse, Duncan Wilson, Hugo Morales Briceno, Pamela Garcia, Victor Zhang, Jessica Qiu, Tomas Kalincik, Neil Mahant, Victor Shue Chung Fung   +8 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source

Lumbosacral Plexopathy: A Single‐Center Review of Etiology, Clinical Presentation, Electrodiagnostic Findings, and Long‐Term Outcomes

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Lumbosacral plexopathy (LSP) results from a spectrum of etiologies and can cause substantial functional impairment. Limited data exist on the relative distribution of etiologies and outcomes across broad tertiary‐care cohorts spanning multiple causes of LSP.
Bradley Ong, Jad El Ahdab, Nicolas Thompson, Yuebing Li, Nirmal Andrapalliyal   +4 more
wiley   +1 more source

Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex

Anesthesiology Research and Practice, 2008
Acquired acute demyelinating peripheral polyneuropathy (AADP) is a general classification of pathologies that could affect secondary the peripheral nervous system. They are characterized by an autoimmune process directed towards myelin.
Davide Cattano, Brian O'connor, Ra'ad Shakir, Francesco Giunta, Mark Palazzo   +4 more
doaj   +1 more source

Clinical reasoning in feline non‐ambulatory tetraparesis or tetraplegia: Which combination of clinical information is useful?

Veterinary Record, EarlyView.
Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley   +1 more source