Results 41 to 50 of about 188,351 (265)

Modern epidemiological features of viral acute intestinal infections in children and adolescents of Sakhalin region

open access: yesЖурнал инфектологии
Objective: to identify modern epidemiological features of viral acute intestinal infections in children and adolescents in the Sakhalin Region.Materials and methods.
E. Yu. Sapega   +2 more
doaj   +1 more source

Acute Intestinal Ischemia in a Patient with COVID-19 Infection

open access: yesThe Korean Journal of Gastroenterology, 2020
The World Health Organization has declared novel coronavirus disease 2019 (COVID-19) a global public health emergency. Although respiratory symptoms predominate in COVID-19, thrombosis can occur in patients with COVID-19. This paper reports a case of an 82-year-old female with a prior medical history of hypertension, diabetes presenting with fever and ...
Balraj Singh   +6 more
openaire   +5 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A new approach to the treatment of acute infection diseases with antibiotic-pectin formulae

open access: yesJournal of Infection in Developing Countries
Introduction: Intestinal infections are a significant health issue; antibiotics are essential in treating acute intestinal infections. However, evidence in the literature shows that the excessive use of antibiotics has created many threats to human ...
Zayniddin K Muhidinov   +6 more
doaj   +1 more source

Some Clinical and Epidemiological Aspects of Rotavirus Infection at the Present Stage

open access: yesAktualʹnaâ Infektologiâ, 2013
The clinical and epidemiological aspects of rotavirus infection in children in Donetsk region at present stage were studied. It is found that among patients with acute intestinal infections and acute respiratory viral infections positive results of ...
A.I. Bobrovitskaya   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Etiological Structure and Features of a Symbiotic Relationship Dominates Agents Acute Intestinal Infections in the North-Eastern Regione of Ukraine

open access: yesЭпидемиология и вакцинопрофилактика, 2015
The article shows a retrospective epidemiological analysis of the incidence of acute intestinal diseases in 2004 – 2013 in Sumy region. The etiological structure was studied.
N. G. Malysh   +3 more
doaj   +1 more source

Evaluation of the Incidence of Rotavirus Infection and the Effectiveness of Vaccination in the Khanty-Mansi Autonomous Ugra District in 2014–2018

open access: yesЭпидемиология и вакцинопрофилактика, 2020
Relevance. Rotavirus infection (RVI) is recognized as the main cause of severe gastroenteritis in children worldwide and leads to 527 000 deaths annually.Aim.
A. A. Girina   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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