Results 1 to 10 of about 12,431 (115)

Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis

Frontiers in Immunology, 2020
Nonalcoholic steatohepatitis (NASH), the advanced stage of nonalcoholic fatty liver disease (NAFLD), is emerging as a leading cause of progressive liver fibrosis and end-stage liver disease.
Haiou Li, Haiou Li, Yunjiao Zhou, Yunjiao Zhou, Haizhou Wang, Haizhou Wang, Meng Zhang, Meng Zhang, Peishan Qiu, Peishan Qiu, Mengna Zhang, Mengna Zhang, Ruike Zhang, Ruike Zhang, Qiu Zhao, Qiu Zhao, Jing Liu, Jing Liu   +17 more
doaj   +1 more source

Role of Smooth Muscle in Intestinal Inflammation

Canadian Journal of Gastroenterology, 1996
The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD).
Stephen M Collins, Islam Khan, Bruce Vallance, Cory Hogaboam, Giovanni Barbara   +4 more
doaj   +1 more source

SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer

Frontiers in Cell and Developmental Biology, 2022
Colorectal cancer (CRC) is the second most lethal malignancy around the world. Limited efficacy of immunotherapy creates an urgent need for development of novel treatment targets.
Hao Wang, Hao Wang, Jinwen Yin, Jinwen Yin, Yuntian Hong, Yuntian Hong, Anli Ren, Anli Ren, Haizhou Wang, Haizhou Wang, Mengting Li, Mengting Li, Qiu Zhao, Qiu Zhao, Congqing Jiang, Congqing Jiang, Lan Liu, Lan Liu   +17 more
doaj   +1 more source

Eosinophilic Intestinal Disease [PDF]

The American Journal of the Medical Sciences, 1907
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openaire   +2 more sources

MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation

Frontiers in Oncology, 2021
BackgroundHepatocellular carcinoma (HCC) remains a major global health burden due to its high prevalence and mortality. Emerging evidence reveals that microRNA (miRNA) plays a vital role in cancer pathogenesis and is widely involved in the regulation of ...
Yinghui Hong, Yinghui Hong, Mingliang Ye, Mingliang Ye, Fan Wang, Fan Wang, Jun Fang, Jun Fang, Chun Wang, Chun Wang, Jie Luo, Jie Luo, Jialiang Liu, Jialiang Liu, Jing Liu, Jing Liu, Lan Liu, Lan Liu, Qiu Zhao, Qiu Zhao, Ying Chang, Ying Chang   +21 more
doaj   +1 more source

The Intestinal Microbiota in Metabolic Disease [PDF]

Nutrients, 2016
Gut bacteria exert beneficial and harmful effects in metabolic diseases as deduced from the comparison of germfree and conventional mice and from fecal transplantation studies. Compositional microbial changes in diseased subjects have been linked to adiposity, type 2 diabetes and dyslipidemia. Promotion of an increased expression of intestinal nutrient
Woting, Anni (Dr.), Blaut, Michael (Prof. Dr.)   +1 more
openaire   +3 more sources

Gut Metagenome as a Potential Diagnostic and Predictive Biomarker in Slow Transit Constipation

Frontiers in Medicine, 2022
Slow transit constipation (STC) is one of the most frequent gastrointestinal diagnoses. In this study, we conducted a quantitative metagenomics study in 118 Chinese individuals.
Hongliang Tian, Hongliang Tian, Chen Ye, Chen Ye, Bo Yang, Bo Yang, Jiaqu Cui, Jiaqu Cui, Zhijun Zheng, Zhijun Zheng, Chunyan Wu, Chunyan Wu, Shailan Zhou, Shailan Zhou, Xiaoqiong Lv, Xiaoqiong Lv, Nan Qin, Nan Qin, Huanlong Qin, Huanlong Qin, Ning Li, Ning Li, Qiyi Chen, Qiyi Chen   +23 more
doaj   +1 more source

The Gut-Brain Axis in IBD: An Investigator’s Perspective

Canadian Journal of Gastroenterology, 1995
Three clinical observations in inflammatory bowel disease (IBD) prompt an examination of the role of gut-brain interactions in the pathophysiology of IBD.
Stephen M Collins, Harvey P Weingarten, Kevin McHugh   +2 more
doaj   +1 more source

Global, regional and national burden of inflammatory bowel disease in females from 1990 to 2021: an analysis of the global burden of disease study 2021

Frontiers in Global Women's Health
Background & aimsThe global incidence of inflammatory bowel disease (IBD) has markedly increased over past several decades. Gender-specific differences have been observed in the epidemiology, manifestation, and prognosis of IBD.
Jingyi Peng, Jingyi Peng, Yuan Yuan, Yuan Yuan, Jie Zhang, Jie Zhang, Yang Ding, Yang Ding, Xingxing He, Xingxing He   +9 more
doaj   +1 more source

Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

Signal Transduction and Targeted Therapy, 2022
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet regimen that mimics the metabolism of the fasting state to induce the production of ketone bodies. The KD has long been established as a remarkably successful dietary
Huiyuan Zhu, Dexi Bi, Youhua Zhang, Cheng Kong, Jiahao Du, Xiawei Wu, Qing Wei, Huanlong Qin   +7 more
doaj   +1 more source