Results 31 to 40 of about 12,431 (115)

Diseases of the Large Intestine

Cleveland Clinic Journal of Medicine, 1932
Diseases and abnormalities of the large intestine are far too numerous to be described in one paper; I shall discuss, therefore, only the more common conditions that may be encountered in the routine examination of the gastro-intestinal tract. The normal contour and position of the colon, as well as many of the abnormal positions that it may assume ...
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An Integrated Dataset of Clinical and Microbial Profiles for Fecal Microbiota Transplantation

Scientific Data
Functional gastrointestinal disorders (FGIDs) are prevalent and burdensome, yet progress in microbiota-targeted therapies such as fecal microbiota transplantation (FMT) has been hampered by the lack of large-scale, integrated datasets.
Sen Yan, Le Wang, Yue Xu, Wanyong Zhu, Ning Li, Qiyi Chen, Long Li   +6 more
doaj   +1 more source

JNK Pathway-Associated Phosphatase/DUSP22 Suppresses CD4+ T-Cell Activation and Th1/Th17-Cell Differentiation and Negatively Correlates with Clinical Activity in Inflammatory Bowel Disease

Frontiers in Immunology, 2017
This study aimed to investigate the role of JNK pathway-associated phosphatase (JKAP) in inflammatory bowel disease (IBD). JKAP expression was analyzed in the intestinal mucosa of 81 IBD patients and 25 healthy controls (HCs) by qPCR and immunoblotting ...
Rui Zhou, Rui Zhou, Ying Chang, Ying Chang, Jing Liu, Jing Liu, Min Chen, Min Chen, Hongling Wang, Hongling Wang, Meifang Huang, Meifang Huang, Shi Liu, Shi Liu, Xiaobing Wang, Xiaobing Wang, Qiu Zhao, Qiu Zhao   +17 more
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Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers

Nature Communications, 2021
Active enhancers are still understudied in colorectal cancers (CRC). Here the authors analyse active enhancers in CRC patients using genomics, transcriptomics, and epigenomics, identifying and validating variant super-enhancer loci as well as KLF3 as a ...
Qing-Lan Li, Xiang Lin, Ya-Li Yu, Lin Chen, Qi-Xin Hu, Meng Chen, Nan Cao, Chen Zhao, Chen-Yu Wang, Cheng-Wei Huang, Lian-Yun Li, Mei Ye, Min Wu   +12 more
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Bowel Sounds Detection Method Based on ResNet-BiLSTM and Attention Mechanism

Zhongguo yiliao qixie zazhi
Bowel sounds can reflect the movement and health status of the gastrointestinal tract. However, the traditional manual auscultation method has subjective deviation and is time-consuming and labor-intensive. In order to better assist doctors in diagnosing
Yali HAO, Xianrong WAN, Congqing JIANG, Xianghai REN, Xiaoming ZHANG, Xiang ZHAI   +5 more
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Chronic Intestinal Inflammation and Intestinal Disease in Dogs [PDF]

Journal of Veterinary Internal Medicine, 2003
Abstract Normal individuals maintain tolerance to the endogenous bacterial flora residing within their alimentary tract, a phenomenon mediated by the gastrointestinal lymphoid tissue. Loss of this tolerance is a key factor in the development of chronic intestinal inflammation. Manifestations of such uncontrolled inflammation in humans
A J, German, E J, Hall, M J, Day
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Risk prediction models for hepatic encephalopathy in patients with liver cirrhosis: a systematic review and meta-analysis

BMC Gastroenterology
Background To conduct a systematic review and meta-analysis of existing prediction models for hepatic encephalopathy (HE) in patients with cirrhosis. Methods Four Chinese and five English databases were searched for studies on prediction models for the ...
Zhile Xiao, Xiaonan Li, Shouquan Dong, Feng Zhou   +3 more
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Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis

European Journal of Medical Research
Background Non-alcoholic fatty liver disease (NAFLD), now referred to as metabolic dysfunction-associated steatotic liver disease (MASLD), is the most prevalent chronic liver disease worldwide.
Zhile Xiao, Xiaonan Li, Jiahong Gong, Feng Zhou   +3 more
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Additive effects of fecal microbiota transplantation and infliximab on gut microbiome and metabolome in refractory inflammatory bowel disease patients

mSystems
Fecal microbiota transplantation (FMT) is an emerging therapy for inflammatory bowel disease (IBD), yet its efficacy in patients refractory to conventional treatments and its underlying mechanisms require further elucidation.
Xinjun Wang, Weijun Wu, Bo Yang, Yunkun Liu, Yue Xu, Le Wang, Xiaoqiong Lv, Junhui Gao, Man Lu, Anqi Yu, Ning Li, Qiyi Chen, Liesheng Lu, Di Zhao   +13 more
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Early Ustekinumab Use Improves Clinical Outcomes in Biologic-Naive Crohn’s Disease Patients: A Retrospective Multicenter Cohort Study in Taiwan

Biomedicines
Background/Objectives: Crohn’s disease (CD) is a progressive condition, and early treatment with infliximab combined with an immunosuppressant within six months has been shown to improve clinical outcomes.
Yen-Cheng Chang, Chiao-Hsiung Chuang, Tien-Yu Huang, Chen-Shuan Chung, Chia-Jung Kuo, Yu-Bin Pan, Puo-Hsien Le   +6 more
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