Results 11 to 20 of about 511,931 (264)
Predicting Distant Metastasis in Young-Onset Colorectal Cancer After Surgery: A Retrospective Study
Frontiers in Oncology, 2022 BackgroundAlthough overall colorectal cancer (CRC) cases have been declining worldwide, there has been an increase in the incidence of the CRC among individuals younger than 50 years old, which is associated with distant metastasis (DM) and poor ...
Jie Cheng +17 more
doaj +1 more source
Frontiers in Oncology, 2023 Plexiform fibromyxoma (PF) is a rare mesenchymal tumor of which the pathogenesis and molecular changes are still unclear. Histologically, it is characterized by a cluster of bland spindle or ovoid cells growing in the mucoid or fibromyxoid stroma rich in
Ziqin Xia +5 more
doaj +1 more source
Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis
Frontiers in Immunology, 2020 Nonalcoholic steatohepatitis (NASH), the advanced stage of nonalcoholic fatty liver disease (NAFLD), is emerging as a leading cause of progressive liver fibrosis and end-stage liver disease.
Haiou Li +17 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Colorectal cancer (CRC) is the second most lethal malignancy around the world. Limited efficacy of immunotherapy creates an urgent need for development of novel treatment targets.
Hao Wang +17 more
doaj +1 more source
Role of Smooth Muscle in Intestinal Inflammation
Canadian Journal of Gastroenterology, 1996 The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD).
Stephen M Collins +4 more
doaj +1 more source
MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation
Frontiers in Oncology, 2021 BackgroundHepatocellular carcinoma (HCC) remains a major global health burden due to its high prevalence and mortality. Emerging evidence reveals that microRNA (miRNA) plays a vital role in cancer pathogenesis and is widely involved in the regulation of ...
Yinghui Hong +21 more
doaj +1 more source
The Intestinal Microbiota in Metabolic Disease [PDF]
Nutrients, 2016 Gut bacteria exert beneficial and harmful effects in metabolic diseases as deduced from the comparison of germfree and conventional mice and from fecal transplantation studies. Compositional microbial changes in diseased subjects have been linked to adiposity, type 2 diabetes and dyslipidemia. Promotion of an increased expression of intestinal nutrient
Woting, Anni (Dr.) +1 more
openaire +3 more sources
Eosinophilic Intestinal Disease [PDF]
The American Journal of the Medical Sciences, 1907 n ...
openaire +2 more sources
Gut Metagenome as a Potential Diagnostic and Predictive Biomarker in Slow Transit Constipation
Frontiers in Medicine, 2022 Slow transit constipation (STC) is one of the most frequent gastrointestinal diagnoses. In this study, we conducted a quantitative metagenomics study in 118 Chinese individuals.
Hongliang Tian +23 more
doaj +1 more source
Intestinal organoids for modelling intestinal development and disease [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2018 Gastrointestinal diseases are becoming increasingly prevalent in developed countries. Immortalized cells and animal models have delivered important but limited insight into the mechanisms that initiate and propagate these diseases.
Kathryn L. Fair +2 more
openaire +2 more sources