Histopathology of the gut in rheumatic diseases [PDF]
, 2018 The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
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Frontiers in Oncology, 2023 Plexiform fibromyxoma (PF) is a rare mesenchymal tumor of which the pathogenesis and molecular changes are still unclear. Histologically, it is characterized by a cluster of bland spindle or ovoid cells growing in the mucoid or fibromyxoid stroma rich in
Ziqin Xia +5 more
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Mechanisms underlying bone loss associated with gut inflammation [PDF]
, 2019 Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
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Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis
Frontiers in Immunology, 2020 Nonalcoholic steatohepatitis (NASH), the advanced stage of nonalcoholic fatty liver disease (NAFLD), is emerging as a leading cause of progressive liver fibrosis and end-stage liver disease.
Haiou Li +17 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Colorectal cancer (CRC) is the second most lethal malignancy around the world. Limited efficacy of immunotherapy creates an urgent need for development of novel treatment targets.
Hao Wang +17 more
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Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip [PDF]
, 2015 The intestinal epithelium is a critical component of the gut barrier. Composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure prevents the transfer of harmful microorganisms, antigens ...
A. J. M. Watson +15 more
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Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis [PDF]
, 2016 The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the ...
Banu, Petrisor +3 more
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MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation
Frontiers in Oncology, 2021 BackgroundHepatocellular carcinoma (HCC) remains a major global health burden due to its high prevalence and mortality. Emerging evidence reveals that microRNA (miRNA) plays a vital role in cancer pathogenesis and is widely involved in the regulation of ...
Yinghui Hong +21 more
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Ly49E Expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases [PDF]
, 2014 The Ly49E NK receptor is a unique inhibitory receptor, presenting with a high degree of conservation among mouse strains and expression on both NK cells and intraepithelial-localised T cells.
Devisscher, Lindsey +11 more
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Role of Smooth Muscle in Intestinal Inflammation
Canadian Journal of Gastroenterology, 1996 The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD).
Stephen M Collins +4 more
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