Results 111 to 120 of about 707,511 (342)

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

Impact of acute kidney injury on major adverse cardiovascular events in intensive care survivors

BJA Open, 2023
Background: Acute kidney injury commonly occurs in patients admitted to ICU. After acute kidney injury, kidney function may not completely recover leading to increased risk of future cardiovascular events.
Mark Andonovic, Jennifer Curle, Jamie P. Traynor, Martin Shaw, Malcolm A.B. Sim, Patrick B. Mark, Kathryn A. Puxty   +6 more
doaj  

Acute kidney injury in children [PDF]

Pediatric Nephrology, 2009
Acute kidney injury (AKI) (previously called acute renal failure) is characterized by a reversible increase in the blood concentration of creatinine and nitrogenous waste products and by the inability of the kidney to regulate fluid and electrolyte homeostasis appropriately. The incidence of AKI in children appears to be increasing, and the etiology of
openaire   +3 more sources

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Acute nephrotoxic and obstructive injury primes the kidney to endotoxin-driven cytokine/chemokine production [PDF]

, 2006
Richard A. Zager, Ali C.M. Johnson, Sherry Y. Hanson, Steve Lund   +3 more
openalex   +1 more source

Timing of Renal‐Replacement Therapy in Patients with Acute Kidney Injury and Sepsis

New England Journal of Medicine, 2018
BACKGROUND Acute kidney injury is the most frequent complication in patients with septic shock and is an independent risk factor for death. Although renal‐replacement therapy is the standard of care for severe acute kidney injury, the ideal time for ...
S. Barbar, R. Clere-Jehl, A. Bourredjem, R. Hernu, Florent Montini, R. Bruyère, C. Lebert, J. Bohé, J. Badie, Jean-Pierre Eraldi, J. Rigaud, B. Levy, S. Siami, G. Louis, L. Bouadma, J. Constantin, E. Mercier, K. Klouche, D. du Cheyron, G. Piton, D. Annane, S. Jaber, Thierry van der Linden, G. Blasco, J. Mira, C. Schwebel, L. Chimot, P. Guiot, Mai-Anh Nay, F. Meziani, Julie Helms, C. Roger, B. Louart, Rémi Trusson, A. Dargent, C. Binquet, J. Quenot   +36 more
semanticscholar   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Characteristics and outcome of pregnancy-related acute kidney injury in a teaching hospital in a low-resource setting: a five-year retrospective review

BMC Nephrology
Background Pregnancy-related kidney injury contributes to a high burden of acute kidney injury in low-resource settings and causes maternal and perinatal morbidity and mortality.
Ephrem Berhe, Hale Teka, Hiluf Ebuy Abraha, Bisrat Tesfay Abera, Marta Abrha Gebru, Tsega Gebremariam, Mohammedtahir Yahya, Birhane Amare, Habtom Tadesse, Hagos Gidey, Fireweyni Tesfay, Mohamedawel Mohamedniguss Ebrahim, Rahel Kidanemariam, Awol Yemane Legesse   +13 more
doaj   +1 more source

De Novo Postinfectious Glomerulonephritis Secondary to Nephritogenic Streptococci as the Cause of Transplant Acute Kidney Injury: A Case Report and Review of the Literature

Case Reports in Transplantation, 2018
Acute kidney injury is common among kidney transplant recipients. Postinfectious glomerulonephritis secondary to nephritogenic streptococci is one of the oldest known etiologies of acute kidney injury in native kidneys but rarely reported among kidney ...
Alexander Bullen, Mita M. Shah
doaj   +1 more source

Acute kidney injury following proton pump inhibitor therapy [PDF]

, 2006
Ursula C. Brewster, Mark A. Perazella
openalex   +1 more source