Results 91 to 100 of about 2,961,482 (290)

Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. [PDF]

, 2011
Innate immune activation via IL-1R or Toll-like receptors (TLR) contibutes to acute kidney injury but its role in tissue remodeling during chronic kidney disease is unclear.
Skuginna Veronika, Mantovani Alberto, S. Clauss, Heni Eka Susanti, R. Allam, Skuginna, Veronika, Clauss, Sebastian, Susanti, Heni Eka, Ramanjaneyulu Allam, H. E. Susanti, Hans-Joachim Anders, Christoph Römmele, Sebastian Clauss, M. Lech, Veronika Skuginna, Clauss Sebastian, Cecilia Garlanda, Lech, Maciej, Ryu, Mi, Lech Maciej, Garlanda Cecilia, C. Garlanda, Ryu Mi, Römmele, Christoph, Heni Eka, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Allam Ramanjaneyulu, Maciej Lech, Cecilia Garl, M. Ryu, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Mi Ryu, Allam, Ramanjaneyulu, Römmele Christoph, C. Römmele, H. J. Anders, Garlanda, Cecilia, V. Skuginna   +41 more
core   +1 more source

Acute kidney injury and renal recovery following Fontan surgeryCentral MessagePerspective

JTCVS Open
Objectives: Acute kidney injury has been described after Fontan surgery, but the duration and outcomes are unknown. We sought to describe the incidence of and risk factors for acute kidney injury and the phenotype of renal recovery, and evaluate the ...
Anna Marosi, Jennifer Conway, MD, Catherine Morgan, MD, Maryna Yaskina, PhD, Rae Foshaug, Alyssa Chappell, BScN, Lindsay Ryerson, MD, Billie-Jean Martin, MD, Alanna Ash, MN, Mohammed Al-Aklabi, MD, Kim Myers, MD, Andrew S. Mackie, MD, SM   +11 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Acute Kidney Injury – An Update [PDF]

, 2015
The syndrome of acute kidney injury (AKI) occurs frequently in hospitalised patients, leading to increased morbidity, mortality, and healthcare expenditure.
Matt Varrier, Richard Fisher, Marlies Ostermann   +2 more
core  

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Acute kidney injury prevalence in patients with colorectal cancer undergoing surgery with curative intent

, 2021
INTRODUCTION: Acute kidney injury (AKI) is a frequent postoperative complication. However, data on the incidence of AKI in patients with colorectal cancer (CRC) undergoing surgery with curative intent are still limited.
Kozlowski, Leszek, Malyszko, Jolanta, Jolanta Malyszko, Leszek Kozlowski   +3 more
core   +1 more source

Temporal trends and clinical characteristics associated with pregnancy-related acute kidney injury in England: a population-based cohort studyAJOG Global Reports at a Glance

AJOG Global Reports
Background: Previous studies have reported an increase in pregnancy-related acute kidney injury, but the underlying reasons and patient characteristics associated with this trend are incompletely understood.
Lisiane F. Leal, PhD, Kristian B. Filion, PhD, Robert W. Platt, PhD, K.S. Joseph, MD, PhD, Laura A. Magee, MD, FRCPC, MSc, FACP, FRCOG, Kate Bramham, MRCP, Anne-Marie Côté, FRCPC, CSPQ, Azar Mehrabadi, PhD   +7 more
doaj   +1 more source

Serum uric acid and acute kidney injury: A mini review

Journal of Advanced Research, 2017
Acute kidney injury causes great morbidity and mortality in both the community and hospital settings. Understanding the etiological factors and the pathophysiological principles resulting in acute kidney injury is essential in prompting appropriate ...
Kai Hahn, Mehmet Kanbay, Miguel A. Lanaspa, Richard J. Johnson, A. Ahsan Ejaz   +4 more
doaj   +1 more source

MicroRNAs in acute kidney injury

Human Genomics, 2016
Acute kidney injury (AKI) is an important clinical issue that is associated with significant morbidity and mortality. Despite research advances over the past decades, the complex pathophysiology of AKI is not fully understood. The regulatory mechanisms underlying post-AKI repair and fibrosis have not been clarified either.
Pei-Chun Fan, Chia-Chun Chen, Yung-Chang Chen, Yu-Sun Chang, Pao-Hsien Chu   +4 more
openaire   +2 more sources

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source