Results 111 to 120 of about 3,163,938 (292)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Role of the macrophage in acute kidney injury [PDF]

, 2010
Ischaemia/Reperfusion Injury (IRI) is the most common cause of acute kidney injury- a devastating clinical problem lacking any specific treatments to promote renal recovery.
Ferenbach, David Arthur
core   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Acute kidney injury in polymorbid patients

The presented clinical observation shows the role of a multidisciplinary team of doctors in the treatment of acute kidney injury (AKI) in a patient suffering from bronchial asthma and metabolic syndrome (morbid obesity, arterial hypertension, type 2 ...
Marina V. Taranova, Elena S. Kamyshova, Elena Yu. Andreeva, Marina V. Lebedeva, Vladimir D. Beketov   +4 more
core   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Characteristics and outcome of pregnancy-related acute kidney injury in a teaching hospital in a low-resource setting: a five-year retrospective review

BMC Nephrology
Background Pregnancy-related kidney injury contributes to a high burden of acute kidney injury in low-resource settings and causes maternal and perinatal morbidity and mortality.
Ephrem Berhe, Hale Teka, Hiluf Ebuy Abraha, Bisrat Tesfay Abera, Marta Abrha Gebru, Tsega Gebremariam, Mohammedtahir Yahya, Birhane Amare, Habtom Tadesse, Hagos Gidey, Fireweyni Tesfay, Mohamedawel Mohamedniguss Ebrahim, Rahel Kidanemariam, Awol Yemane Legesse   +13 more
doaj   +1 more source

Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Bothrops are one of the most common medically important snakes found in Latin America. Its venom is predominantly hemotoxic and proteolytic, which means that local lesion (edema and redness) and hemorrhagic symptoms are recurrent in envenoming by this ...
Polianna Lemos Moura Moreira Albuquerque, José Hicaro Hellano Gonçalves Lima Paiva, Alice Maria Costa Martins, Gdayllon Cavalcante Meneses, Geraldo Bezerra da Silva Júnior, Nicholas Buckley, Elizabeth De Francesco Daher   +6 more
doaj   +2 more sources

Increased risk of acute kidney injury in patients undergoing tricuspid valve surgery [PDF]

, 2013
We aimed to determine which patients undergoing tricuspid valve (TV) surgery are at increased risk for acute kidney injury (AKI)
Englberger, Lars, Abel, Martin D, Suri, Rakesh M, Connolly, Heidi M, Li, Zhuo, Greason, Kevin L, Dearani, Joseph A, Schaff, Hartzell V   +7 more
core   +2 more sources

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Incidence and Hazard ratio for acute kidney injury and acute kidney injury -associated risk factor.

, 2016
Incidence and Hazard ratio for acute kidney injury and acute kidney injury -associated risk factor.
Chia-Hung Kao (173343), Yu-Guang Chen (797698), Te-Yu Lin (2822420), Cheng-Li Lin (388859)   +3 more
core   +1 more source