Results 241 to 250 of about 707,511 (342)

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

The relationship between lactate/albumin ratio and prognosis in children with acute kidney injury. [PDF]

PLoS One
Zhang R, Feng W, Feng K, Sun F, Ren X, Wang H, Yang R.   +6 more
europepmc   +1 more source

Acute kidney injury in patients with sepsis: a contemporary analysis [PDF]

, 2008
José António Lopes, Sofía Jorge, Cristina Resina, Carla Santos, Álvaro Pereira, José Neves, Francisco Antunes, Mateus Martins Prata   +7 more
openalex   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

The Safety of Apixaban Compared to Warfarin in Hospitalized Patients with Acute Kidney Injury. [PDF]

J Clin Med
Al Yami MS, Alfehaid L, Alshehri AM, Alqahtani N, Almuaither G, Alonazi SH, Alzahrani MY, Badawoud AM, Almohammed OA.   +8 more
europepmc   +1 more source

Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study [PDF]

, 2008
Ingrid Steinvall, Zoltán Bak, Folke Sjöberg   +2 more
openalex   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Risk factors of acute kidney injury in children with diabetic ketoacidosis. [PDF]

BMC Nephrol
Alyahyawi N, Alghamdi D, Almahmoudi A, Sandokji I, Bokhari S, Safdar OY, Shalaby M, Shazly M, Kari JA.   +8 more
europepmc   +1 more source

Contribution of intrarenal cells to cellular repair after acute kidney injury: subcapsular implantation technique

, 2008
Lisa M. Curtis, SF Chen, Bo Chen, Anupam Agarwal, Christopher A. Klug, Paul W. Sanders   +5 more
openalex   +2 more sources

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source