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Clinical Medicine, 2009 The term acute kidney injury (AKI) has now replaced the term acute renal failure (ARF) and represents the entire spectrum of the latter. It is best characterised by a rapid decline in kidney function over hours to weeks with the retention of nitrogenous waste products and creatinine.
M. Rosner
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Intensive Care Medicine, 2023
Acute kidney injury (AKI) has been shown to occur commonly in hospitalized children. AKI is associated with multiple complications, including elevated blood urea nitrogen level, electrolyte dyscrasias, acidosis, and fluid balance disorders. During the past 10 years, multiple multicenter studies have shown that AKI occurs commonly and is associated with
Marlies Ostermann +2 more
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Acute kidney injury (AKI) has been shown to occur commonly in hospitalized children. AKI is associated with multiple complications, including elevated blood urea nitrogen level, electrolyte dyscrasias, acidosis, and fluid balance disorders. During the past 10 years, multiple multicenter studies have shown that AKI occurs commonly and is associated with
Marlies Ostermann +2 more
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Global epidemiology and outcomes of acute kidney injury
Nature Reviews Nephrology, 2018Eric A J Hoste +2 more
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Annals of Internal Medicine, 2018
Acute kidney injury (AKI) most commonly occurs in the hospital setting, and hospital-acquired AKI accounts for 22% of all AKI cases worldwide. AKI causes 2 million deaths per year, and 50% of critically ill patients develop AKI. AKIs include prerenal, intrarenal, and postrenal causes.
Joana, Gameiro +2 more
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Acute kidney injury (AKI) most commonly occurs in the hospital setting, and hospital-acquired AKI accounts for 22% of all AKI cases worldwide. AKI causes 2 million deaths per year, and 50% of critically ill patients develop AKI. AKIs include prerenal, intrarenal, and postrenal causes.
Joana, Gameiro +2 more
+7 more sources
Critical Care Medicine, 2008
Diagnosis and classification of acute pathology in the kidney are major clinical problems. Azotemia and oliguria represent not only disease but normal responses of the kidney to extracellular volume depletion or decreased renal blood flow. Changes in urine output and glomerular filtration rate are therefore neither necessary nor sufficient for the ...
Norbert, Lameire +2 more
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Diagnosis and classification of acute pathology in the kidney are major clinical problems. Azotemia and oliguria represent not only disease but normal responses of the kidney to extracellular volume depletion or decreased renal blood flow. Changes in urine output and glomerular filtration rate are therefore neither necessary nor sufficient for the ...
Norbert, Lameire +2 more
openaire +4 more sources
Annals of Internal Medicine, 2017
Acute kidney injury is a heterogeneous group of conditions characterized by a sudden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentration or oliguria, and classified by stage and cause. This type of injury occurs in approximately 20% of hospitalized patients, with major complications including volume ...
Andrew S, Levey, Matthew T, James
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Acute kidney injury is a heterogeneous group of conditions characterized by a sudden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentration or oliguria, and classified by stage and cause. This type of injury occurs in approximately 20% of hospitalized patients, with major complications including volume ...
Andrew S, Levey, Matthew T, James
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Science Signaling, 2022
The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) regulates cell death. We sought to determine whether DNA-PKcs played a role in the tubular damage that occurs during acute kidney injury (AKI) induced by LPS injection (to mimic sepsis ...
Shiyuan Wang +6 more
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The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) regulates cell death. We sought to determine whether DNA-PKcs played a role in the tubular damage that occurs during acute kidney injury (AKI) induced by LPS injection (to mimic sepsis ...
Shiyuan Wang +6 more
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Critical Care Clinics, 2021
Acute kidney injury (AKI) is a syndrome of impaired kidney function associated with reduced survival and increased morbidity. International consensus criteria were developed based on changes in serum creatinine and urine output. Based on these definitions, epidemiologic studies have shown strong associations with clinical outcomes including death and ...
Siddharth, Verma, John A, Kellum
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Acute kidney injury (AKI) is a syndrome of impaired kidney function associated with reduced survival and increased morbidity. International consensus criteria were developed based on changes in serum creatinine and urine output. Based on these definitions, epidemiologic studies have shown strong associations with clinical outcomes including death and ...
Siddharth, Verma, John A, Kellum
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Current concepts and advances in biomarkers of acute kidney injury
Critical reviews in clinical laboratory sciences, 2021Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition remains based on changes in serum creatinine and urinary output that do not specifically represent tubular function or injury and that have significant ...
Yumeng Wen, C. Parikh
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