Results 31 to 40 of about 501,514 (307)

Acute Kidney Injury and Electrolyte Abnormalities After Chimeric Antigen Receptor T-Cell (CAR-T) Therapy for Diffuse Large B-Cell Lymphoma.

American Journal of Kidney Diseases, 2020
RATIONALE & OBJECTIVE Cytokine release syndrome is a well-known complication of chimeric antigen receptor T-cell (CAR-T) therapy and can lead to multiorgan dysfunction. However, the nephrotoxicity of CAR-T therapy is unknown. We aimed to characterize the
Shruti Gupta, H. Seethapathy, I. Strohbehn, M. Frigault, E. O’Donnell, C. Jacobson, Shveta S. Motwani, S. Parikh, G. Curhan, K. Reynolds, D. Leaf, M. Sise   +11 more
semanticscholar   +1 more source

Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]

, 2015
Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond, Vanmassenhove, Jill   +4 more
core   +2 more sources

Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Clinical Kidney Journal, 2020
Background Acute kidney injury (AKI) can affect hospitalized patients with coronavirus disease 2019 (COVID-19), with estimates ranging between 0.5% and 40%.
Edouard L. Fu, Roemer J. Janse, Y. de Jong, Vera H W van der Endt, J. Milders, E. M. van der Willik, E. D. de Rooij, O. Dekkers, J. Rotmans, M. van Diepen   +9 more
semanticscholar   +1 more source

Acute kidney injury in critically ill cancer patients : an update [PDF]

, 2016
Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond   +3 more
core   +2 more sources

Potential targeted therapy and diagnosis based on novel insight into growth factors, receptors, and downstream effectors in acute kidney injury and acute kidney injury-chronic kidney disease progression

Signal Transduction and Targeted Therapy, 2020
Acute kidney injury (AKI) is defined as a rapid decline in renal function and is characterized by excessive renal inflammation and programmed death of resident cells.
Li Gao, Xiang Zhong, Juan Jin, Jun Li, Xiao-ming Meng   +4 more
semanticscholar   +1 more source

Use of Estimating Equations for Dosing Antimicrobials in Patients with Acute Kidney Injury Not Receiving Renal Replacement Therapy. [PDF]

, 2018
Acute kidney injury (AKI) can potentially lead to the accumulation of antimicrobial drugs with significant renal clearance. Drug dosing adjustments are commonly made using the Cockcroft-Gault estimate of creatinine clearance (CLcr). The Modified Jelliffe
Awdishu, Linda, Bouchard, Josée, Chertow, Glenn M, Connor, Ana Isabel, Macedo, Etienne, Mehta, Ravindra L   +5 more
core   +2 more sources

Systemic hypertension in cats with acute kidney injury [PDF]

, 2017
Retrospective study of cats presenting to the Queen Mother Hospital for Animals, Royal Veterinary College with acute kidney injury between 2007 and 2015.
Acierno, Basile, Behrend, Belew, Bijsmans, Braun, Brown, Campese, Chertow, Chetboul, Geigy, Harison, Hoste, Hoste, Jacob, Jepson, Jepson, Klag, Kletzmayr, Lee, Maggio, Monaghan, Pouchelon, Ravera, Segev, Stiles, Syme, Uchino, Wehner   +28 more
core   +2 more sources

Acute Kidney Injury after CAR-T Cell Therapy: Low Incidence and Rapid Recovery.

Biology of Blood and Marrow Transplantation, 2020
Chimeric antigen receptor (CAR) T cell therapy using engineered cytotoxic T cells has shown promising responses in various hematological malignancies. Cytokine release syndrome (CRS) and immune effector cell associated neurological syndrome (ICANS) are ...
V. Gutgarts, T. Jain, Junting Zheng, M. Maloy, J. Ruiz, M. Pennisi, E. Jaimes, M. Perales, Jaffer Sathick   +8 more
semanticscholar   +1 more source

Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism. [PDF]

, 2014
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
Abosaif, Andres-Hernando, Andres-Hernando, Barbara Philips, Boucher, Bougle, Brown, Chan, Chawla, Chung, Doi, Dowling, Dreisbach, Dreisbach, English, Fadillioglu, Gardiner, Gertz, Golab, Group, Gurley, Hassoun, Heinemeyer, Heinemeyer, Iain MacPhee, Izuwa, John Dixon, Karim, Katie Lane, Kirwan, Kirwan, Klein, Kramer, Krueger, Kunihara, Kunuzova, Lane, Lash, Leblanc, Lee, Lee, Lohr, Martyn, Mastorakos, Meier-Hellmann, Michaud, Michaud, Miyazawa, Muntane-Relat, Murakami, Naud, Naud, Nicholson, Nolin, Nolin, Okabe, Okabe, Okabe, Owen, O’Shaunessy, Park, Park, Philips, Power, Schneider, Serteser, Shi, Shibata, Smith, Soni, Spapen, Srinivas, Sun, Tanabe, Tian, Venkatesh, Wang, Whelton, Wilkinson, Wilson, Yamaguchi, Yoshitani, Yu   +82 more
core   +2 more sources

Novel regenerative therapy for acute kidney injury [PDF]

Renal Replacement Therapy, 2016
Acute kidney injury (AKI) is a renal disease that is associated with high mortality. Current treatments mostly rely on supportive therapies and do not directly target the disease. Regenerative medicine, however, offers potentially direct AKI therapy through two strategies: cell transplantation and kidney reconstruction.
Toyohara, Takafumi, Osafune, Kenji
openaire   +1 more source