Results 1 to 10 of about 1,378,904 (356)

Chrononutrition in Critical Illness. [PDF]

Nutr Rev
Abstract Circadian rhythms in humans are biological rhythms that regulate various physiological processes within a 24-hour time frame. Critical illness can disrupt the circadian rhythm, as can environmental and clinical factors, including altered light exposure, organ replacement therapies, disrupted sleep–wake cycles, noise, continuous ...
Sagun E, Akyol A, Kaymak C.
europepmc   +3 more sources

Redefining critical illness

Nature Medicine, 2022
Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
Maslove, David M, Tang, Benjamin, Shankar-Hari, Manu, Lawler, Patrick R, Angus, Derek C, Baillie, J Kenneth, Baron, Rebecca M, Bauer, Michael, Buchman, Timothy G, Calfee, Carolyn S, Dos Santos, Claudia C, Giamarellos-Bourboulis, Evangelos J, Gordon, Anthony C, Kellum, John A, Knight, Julian C, Leligdowicz, Aleksandra, McAuley, Daniel F, McLean, Anthony S, Menon, David K, Meyer, Nuala J, Moldawer, Lyle L, Reddy, Kiran, Reilly, John P, Russell, James A, Sevransky, Jonathan E, Seymour, Christopher W, Shapiro, Nathan I, Singer, Mervyn, Summers, Charlotte, Sweeney, Timothy E, Thompson, B Taylor, van der Poll, Tom, Venkatesh, Balasubramanian, Walley, Keith R, Walsh, Timothy S, Ware, Lorraine B, Wong, Hector R, Zador, Zsolt E, Marshall, John C   +38 more
openaire   +10 more sources

Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial

Critical Care, 2023
Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI).
Mina F. Nordness, Amelia W. Maiga, Laura D. Wilson, Tatsuki Koyama, Erika L. Rivera, Shayan Rakhit, Michael de Riesthal, Cari L. Motuzas, Madison R. Cook, Deepak K. Gupta, James C. Jackson, Shawniqua Williams Roberson, William J. Meurer, Roger J. Lewis, Geoffrey T. Manley, Pratik P. Pandharipande, Mayur B. Patel   +16 more
doaj   +1 more source

Instruments Assessing Cognitive Impairment in Survivors of Critical Illness and Reporting of Race Norms: A Systematic Review

Critical Care Explorations, 2022
OBJECTIVE:. To conduct a systematic review to summarize cognitive instruments being used in long-term outcome studies of survivors of adult critical illness, as well as evaluate whether these measures are reported as using patient demographic norms ...
Rameela Raman, PhD, Spencer J. DesAutels, MLIS, Alana M. Lauck, MS, Alexa M. Scher, BA, Rachel L. Walden, MLIS, Amy L. Kiehl, MA, Erin M. Collar, MPH, E. Wesley Ely, MD, MPH, Pratik P. Pandharipande, MD, MSCI, James C. Jackson, PsyD   +9 more
doaj   +1 more source

Effects of non-pharmacological interventions on sleep in patients with critical illness: a systematic review and network meta-analysis. [PDF]

Sci Rep
Matsuura Y, Kita E, Taneda Y, Matsuda M, Kataoka M, Masuya M, Fukuroku K.   +6 more
europepmc   +2 more sources

Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review

Trials, 2021
Background There is a growing number of randomized controlled trials (RCTs) evaluating interventions to prevent or treat delirium in the intensive care unit (ICU).
Elizabeth Colantuoni, Mounica Koneru, Narjes Akhlaghi, Ximin Li, Mohamed D. Hashem, Victor D. Dinglas, Karin J. Neufeld, Michael O. Harhay, Dale M. Needham   +8 more
doaj   +1 more source

Chronic Critical Illness [PDF]

American Journal of Respiratory and Critical Care Medicine, 2010
Although advances in intensive care have enabled more patients to survive an acute critical illness, they also have created a large and growing population of chronically critically ill patients with prolonged dependence on mechanical ventilation and other intensive care therapies.
Judith E, Nelson, Christopher E, Cox, Aluko A, Hope, Shannon S, Carson   +3 more
openaire   +2 more sources

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

Critical Care, 2017
Background Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60 − 70 years ...
Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill   +7 more
doaj   +1 more source

AKI patients have worse long-term outcomes, especially in the immediate post-ICU period [PDF]

, 2012
Acute kidney injury (AKI) is associated with worse outcome in the acute phase of acute illness but also in the chronic phase. In a large Danish study in this issue of Critical Care, 1-year mortality was higher in patients with AKI than in patients ...
De Corte, Wouter, Hoste, Eric
core   +2 more sources

Critical illness polyneuromyopathy [PDF]

Canadian Medical Association Journal, 2016
Flaccid weakness develops in the limbs or respiratory muscles; the latter may present as difficulty in weaning from ventilation. Sensation may be reduced to pinprick. Reflexes may be present in the acute phase of the illness but are generally reduced or absent.
Cameron, Cunningham, Heather, Finlayson
openaire   +2 more sources